School of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Department of Rehabilitation Medicine, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai 200137, China.
Can Respir J. 2021 Jan 29;2021:1904231. doi: 10.1155/2021/1904231. eCollection 2021.
This systematic review aimed to investigate the effect of different breathing exercises on respiratory muscle function, 6-minute walk test (6MWT), and quality of life (QoL) in patients with chronic obstructive pulmonary disease (COPD).
We searched online databases including PubMed, Embase, Web of Science, Cochrane Library, and Ovid for randomized controlled trials that assessed the efficacy of breathing exercises on patients with COPD. Patient outcome parameters included changes in respiratory muscle function, 6MWT, and QoL. The Cochrane Collaboration tool was used to assess the risk of bias for each included study. Subgroup analyses concerning different interventions and outcome measurements were conducted as necessary. PROSPERO registration number is CRD42018118367.
A total of 17 studies were included for final analysis. Meta-analysis based on the relevant studies showed that breathing exercises had a significant total effect on pulmonary function PImax (mean difference (MD) = 8.65, 95% confidence interval (CI) 3.13-14.16, =0.002), as well as 6MWT (MD = 27.70, 95% CI 5.45-49.94, =0.01) in patients with COPD.
This systematic review summarized the use of breathing exercises for treating patients with COPD. Breathing exercises were found to be an effective tool for treating patients with COPD by improving inspiratory muscle strength and 6MWT. However, breathing exercises showed no significant improvements on the QoL of patients with COPD.
本系统评价旨在探讨不同呼吸锻炼对慢性阻塞性肺疾病（COPD）患者呼吸肌功能、6 分钟步行试验（6MWT）和生活质量（QoL）的影响。
我们检索了包括 PubMed、Embase、Web of Science、Cochrane 图书馆和 Ovid 在内的在线数据库，以评估呼吸锻炼对 COPD 患者疗效的随机对照试验。患者结局参数包括呼吸肌功能、6MWT 和 QoL 的变化。使用 Cochrane 协作工具评估每个纳入研究的偏倚风险。必要时进行了针对不同干预措施和结局测量的亚组分析。PROSPERO 注册号为 CRD42018118367。
共有 17 项研究纳入最终分析。基于相关研究的荟萃分析显示，呼吸锻炼对肺功能 PImax（均数差（MD）=8.65，95%置信区间（CI）3.13-14.16，=0.002）以及 COPD 患者的 6MWT（MD=27.70，95%CI 5.45-49.94，=0.01）有显著的总效应。
本系统评价总结了呼吸锻炼治疗 COPD 患者的应用。呼吸锻炼被发现是治疗 COPD 患者的有效工具，可改善吸气肌力量和 6MWT。然而，呼吸锻炼对 COPD 患者的 QoL 没有显著改善。
