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从波斯尼亚和黑塞哥维那 COVID-19 患者中分离的 SARS-CoV-2 的系统发育模式:优化未来分子和流行病学方法的经验教训。

Phylogenetic pattern of SARS-CoV-2 from COVID-19 patients from Bosnia and Herzegovina: lessons learned to optimize future molecular and epidemiological approaches.

机构信息

Veterinary faculty of University of Sarajevo, Sarajevo, Bosnia and Herzegovina.

ALEA Genetic Center, Sarajevo, Bosnia and Herzegovina.

出版信息

Bosn J Basic Med Sci. 2021 Aug 1;21(4):484-487. doi: 10.17305/bjbms.2020.5381.

Abstract

This is the first report of molecular and epidemiology findings from Bosnia and Herzegovina related to ongoing severe acute respiratory syndrome coronavirus 2 epidemic. Whole genome sequence of four samples from coronavirus disease 2019 (COVID-19) outbreaks was done in two laboratories in Bosnia and Herzegovina (Veterinary Faculty Sarajevo and Alea Genetic Center). All four BiH sequences cluster mainly with European ones (Italy, Austria, France, Sweden, Cyprus, and England). The constructed phylogenetic tree indicates possible multiple independent introduction events. The data presented contribute to a better understanding of COVID-19 in the current reemergence of the disease.

摘要

这是波黑首例与正在发生的严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)疫情相关的分子和流行病学研究结果报告。在波黑的两个实验室(萨拉热窝兽医系和 Alea 遗传中心)对来自 2019 年冠状病毒病(COVID-19)疫情的四个样本进行了全基因组测序。四个波黑序列主要与欧洲序列(意大利、奥地利、法国、瑞典、塞浦路斯和英国)聚类。构建的系统发育树表明可能存在多个独立的传入事件。所提供的数据有助于更好地了解当前疾病再次出现时的 COVID-19 情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72c4/8292857/e17c4996be25/BJBMS-21-484-g001.jpg

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