意大利的 SARS-COV-2 的基因组特征和系统进化分析。
Genomic characterization and phylogenetic analysis of SARS-COV-2 in Italy.
机构信息
Department of Biomedical and Clinical Sciences Luigi Sacco, University of Milan, Milan, Italy.
EpiSoMi CRC-Coordinated Research Center, University of Milan, Milan, Italy.
出版信息
J Med Virol. 2020 Sep;92(9):1637-1640. doi: 10.1002/jmv.25794. Epub 2020 Apr 10.
Abstract
This report describes the isolation, molecular characterization, and phylogenetic analysis of the first three complete genomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolated from three patients involved in the first outbreak of COVID-19 in Lombardy, Italy. Early molecular epidemiological tracing suggests that SARS-CoV-2 was present in Italy weeks before the first reported cases of infection.
摘要
本报告描述了从意大利伦巴第首次 COVID-19 暴发中涉及的 3 名患者身上分离出的、首批 3 株严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）的全基因组的分离、分子特征鉴定和系统进化分析。早期的分子流行病学溯源提示，在意大利首例感染病例报告之前，SARS-CoV-2 已存在数周。
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