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磁控胶囊胃镜筛查上消化道癌:一项可行性研究。

Screening for upper gastrointestinal cancers with magnetically controlled capsule gastroscopy: a feasibility study.

机构信息

Department of Gastroenterology, Laboratory of Translational Gastroenterology, and Robot Engineering Laboratory for Precise Diagnosis and Therapy of GI Tumor, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Jinan, Shandong, China.

Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.

出版信息

Endoscopy. 2021 Sep;53(9):914-919. doi: 10.1055/a-1333-2120. Epub 2021 Feb 12.

DOI:10.1055/a-1333-2120
PMID:33580488
Abstract

BACKGROUND

The medical consortium is an intensive and disease-specific association that integrates tertiary public hospitals and medical examination centers in China. We aimed to evaluate the feasibility of the medical consortium for screening upper gastrointestinal (GI) cancers (MCSC) by magnetically controlled capsule gastroscopy (MCCG).

METHODS

6627 asymptomatic subjects underwent MCCG as part of health check-ups in the MCSC between March and November 2018. Relevant clinical data were collected and analyzed.

RESULTS

The MCSC detected 32 patients with upper GI cancer (0.48 %) confirmed by pathology. The detection rate of early gastric cancer was 16.67 % (4 /24). Gastric polyps, ulcers, and submucosal tumors were found in 15.54 %, 3.76 %, and 3.17 % of subjects, respectively. The whole GI preparation and operation process were well tolerated.

CONCLUSIONS

The MCSC was a feasible model for upper GI cancer screening, especially for asymptomatic subjects. Further prospective studies with better operational quality control are warranted.

摘要

背景

医疗联盟是一个集中且针对特定疾病的协会,整合了中国的三级公立医院和体检中心。我们旨在评估磁控胶囊胃镜(MCCG)在上消化道(GI)癌症筛查中的医疗联盟(MCSC)的可行性。

方法

2018 年 3 月至 11 月,6627 名无症状受试者在 MCSC 中接受 MCCG 作为健康检查的一部分。收集并分析相关临床数据。

结果

MCSC 通过病理检查确诊 32 例上消化道癌(0.48%)。早期胃癌的检出率为 16.67%(4/24)。分别有 15.54%、3.76%和 3.17%的受试者发现胃息肉、溃疡和黏膜下肿瘤。整个胃肠道准备和操作过程均耐受良好。

结论

MCSC 是上消化道癌症筛查的一种可行模式,特别是对无症状受试者。需要进一步进行操作质量控制更好的前瞻性研究。

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