Research Unit, Sportive Performance and Physical Rehabilitation, High Institute of Sports and Physical Education of Kef, University of Jendouba, Kef, Tunisia.
Higher Institute of Sport and Physical Education of Ksar Said, University of "La Manouba", Manouba, Tunisia.
Horm Mol Biol Clin Investig. 2020 Nov 25;41(4):hmbci-2020-0031. doi: 10.1515/hmbci-2020-0031.
To investigate the effects of 12-week high-intensity- (HIIT) moderate-intensity-interval training (MIIT) on thyroid stimulating hormone (TSH) and thyroxine (T4) and insulin-resistance in overweight/obese adolescent girls.
Twenty four adolescent girls (age 16.5±1.36 yrs) were randomly allocated into three groups: (1) HIIT (2 blocks per session of 6-8 bouts of 30 s runs at 100-110% maximal aerobic speed (MAS), with 30 s active recovery between bouts at 50% MAS; n=8), (2) MIIT (2 blocks per session of 6-8 bouts of 30 s runs at 70-80% MAS, with 30 s active recovery between bouts at 50% MAS; n=8) and (3) control group (no exercise, n=8). Each training groups engaged in three sessions per week during three months. Anthropometric parameters, aerobic capacity, homeostasis model assessment index for insulin resistance (HOMA-IR) as well as plasma TSH and T4 levels were assessed in all subjects before- and after-training.
Following both training programs, body mass, body mass index Z-score, waist circumference and body fat decreased, while aerobic capacity increased. However, TSH and T4 concentrations decreased only after the HIIT (-30.47%, p<0.05, ES=1.42 and -12.86%, p<0.05, ES=1.18; respectively). The HOMA-IR decreased in both training groups (-26.25%, p<0.05, ES=1.87 for MIIT and -21.72%, p<0.05, ES=2.14 for HIIT).
Twelve weeks of HIIT was effective in reducing circulating TSH and T4 levels, unlike MIIT, in overweight/obese adolescent girls. These findings indicated that the stimulation of pituitary-thyroid function is more sensitive to training intensity than training duration. Further studies are needed to confirm this conclusion.
研究 12 周高强度间歇训练（HIIT）和中等强度间歇训练（MIIT）对超重/肥胖青少年女孩促甲状腺激素（TSH）和甲状腺素（T4）以及胰岛素抵抗的影响。
将 24 名青少年女孩（年龄 16.5±1.36 岁）随机分为三组：（1）HIIT 组（每节训练 2 个单元，每个单元 6-8 个 30 秒的冲刺，速度为最大有氧速度的 100-110%（MAS），每个冲刺之间休息 30 秒，速度为 MAS 的 50%；n=8），（2）MIIT 组（每节训练 2 个单元，每个单元 6-8 个 30 秒的冲刺，速度为 70-80% MAS，每个冲刺之间休息 30 秒，速度为 MAS 的 50%；n=8）和（3）对照组（不运动，n=8）。每个训练组在三个月内每周进行三次训练。所有受试者在训练前后均评估了身体成分、有氧能力、胰岛素抵抗的稳态模型评估指数（HOMA-IR）以及血浆 TSH 和 T4 水平。
在进行两种训练后，体重、体重指数 Z 评分、腰围和体脂减少，而有氧能力增加。然而，只有 HIIT 后 TSH 和 T4 浓度降低（-30.47%，p<0.05，ES=1.42 和-12.86%，p<0.05，ES=1.18；分别）。两种训练组的 HOMA-IR 均降低（MIIT 组为-26.25%，p<0.05，ES=1.87；HIIT 组为-21.72%，p<0.05，ES=2.14）。
与 MIIT 不同，12 周的 HIIT 可有效降低超重/肥胖青少年女孩的循环 TSH 和 T4 水平。这些发现表明，垂体-甲状腺功能的刺激对训练强度比训练时间更敏感。需要进一步的研究来证实这一结论。
