College of Food Science and Engineering, Northwest A&F University, Yangling 712100, Shaanxi, China.
College of Food Science and Engineering, Northwest A&F University, Yangling 712100, Shaanxi, China.
Food Chem. 2021 Jul 1;349:129202. doi: 10.1016/j.foodchem.2021.129202. Epub 2021 Feb 4.
In this work, we propose a electrochemical enzyme-free glucose sensor by direct growth of conductive Ni/Co bimetal MOF on carbon cloth [Ni/Co(HHTP)MOF/CC] via a facile hydrothermal method. Due to excellent conductivity between Ni/Co(HHTP)MOF and CC, synergic catalytic effect of Ni and Co elements, the Ni/Co(HHTP)MOF/CC not only provides larger surface area and more effective active sites, but also boosts the charge transports and electro-catalytic performance. Under optimized conditions, the Ni/Co(HHTP)MOF/CC shows excellent activity with a linear range of 0.3 μM-2.312 mM, a low detection limit of 100 nM (S/N = 3), a fast response time of 2 s and a high sensitivity of 3250 μA mM cm. Furthermore, the Ni/Co(HHTP)MOF/CC was successfully applied for the detection of glucose in real serum and beverages with competitive performances. This facile and cost-effective method provides a novel strategy for monitoring of glucose in biological and food samples.
在这项工作中，我们通过简便的水热法直接在碳布上生长导电的 Ni/Co 双金属 MOF [Ni/Co(HHTP)MOF/CC]，提出了一种电化学无酶葡萄糖传感器。由于 Ni/Co(HHTP)MOF 与 CC 之间具有优异的导电性、Ni 和 Co 元素的协同催化作用，Ni/Co(HHTP)MOF/CC 不仅提供了更大的表面积和更多有效的活性位点，而且还促进了电荷传输和电催化性能。在优化条件下，Ni/Co(HHTP)MOF/CC 表现出优异的活性，线性范围为 0.3 μM-2.312 mM，检测限低至 100 nM（S/N = 3），响应时间快至 2 s，灵敏度高至 3250 μA mM cm。此外，Ni/Co(HHTP)MOF/CC 成功地应用于实际血清和饮料中葡萄糖的检测，具有竞争性的性能。这种简便且具有成本效益的方法为生物和食品样品中葡萄糖的监测提供了一种新策略。
