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生物恐怖主义制剂的电化学检测:关于A类生物武器生物安全计划中传感器的检测、诊断及应用的综述

The electrochemical detection of bioterrorism agents: a review of the detection, diagnostics, and implementation of sensors in biosafety programs for Class A bioweapons.

作者信息

O'Brien Connor, Varty Kathleen, Ignaszak Anna

机构信息

Department of Chemistry, University of New Brunswick, 30 Dineen Drive, Fredericton, NB E3B 5A3 Canada.

出版信息

Microsyst Nanoeng. 2021 Feb 10;7:16. doi: 10.1038/s41378-021-00242-5. eCollection 2021.

Abstract

During the past year, disease has shown us the iron grip it can hold over a population of people. Health systems can be overwhelmed, economies can be brought into recession, and many people can be harmed or killed. When weaponized, diseases can be manipulated to create a detriment to health while becoming an economic burden on any society. It is consequently prudent that easy detection of bioweapons is available to governments for protecting their people. Electrochemical sensing displays many distinct advantages, such as its low limit of detection, low cost to run, rapid generation of results, and in many instances portability. We therefore present a wide array of electrochemical sensing platforms currently being fabricated, a brief summary of Class A bioweapons, and the potential future of bioweapon detection and biosafety.

摘要

在过去的一年里,疾病向我们展示了它对人群所能施加的强大控制。卫生系统可能不堪重负,经济可能陷入衰退,许多人可能受到伤害或死亡。当被武器化时,疾病可被操纵以损害健康,同时成为任何社会的经济负担。因此,政府能够轻松检测生物武器以保护其人民是审慎之举。电化学传感具有许多显著优势,例如其检测限低、运行成本低、结果生成迅速,而且在许多情况下具有便携性。因此,我们展示了目前正在制造的各种各样的电化学传感平台,简要概述了A类生物武器,以及生物武器检测和生物安全的潜在未来。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e869/8433344/e0e785880637/41378_2021_242_Fig1_HTML.jpg

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