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身体活动与阻塞性睡眠呼吸暂停风险之间的关联。

Association between physical activity and risk of obstructive sleep apnea.

作者信息

Duan Xueru, Zheng Murui, He Shangfei, Lao Lixian, Huang Jun, Zhao Wenjing, Lao Xiang Qian, Deng Hai, Liu Xudong

机构信息

Department of Epidemiology, School of Public Health, Sun Yat-sen University, 2F, Block 20, No.74, Zhongshan Second Road, Guangzhou, 510080, China.

Guangzhou Center for Disease Control and Prevention, Guangzhou, 510440, China.

出版信息

Sleep Breath. 2021 Dec;25(4):1925-1934. doi: 10.1007/s11325-021-02318-y. Epub 2021 Feb 13.

Abstract

PURPOSE

This aim of this study was to investigate the association of physical activity with OSA risk among adult Chinese.

METHODS

Participants were selected from baseline survey of the Guangzhou Heart Study. OSA was ascertained by using Berlin Questionnaire, and the physical activity, including leisure-time physical activity (LTPA), occupational activity, and transport activity, was measured with modified Global Physical Activity Questionnaire. Principal component analysis was used to extract the patterns of LTPA with varimax orthogonal transformation. Odds ratios (OR) with 95% confidence interval (95% CI) were calculated by using the logistic regression method.

RESULTS

For all 9733 participants, aged 35 to 74 years, LTPA (high vs. inactive, OR: 0.81, 95% CI: 0.64-1.03), occupational activity (vigorous vs. retirement, OR:1.28, 95% CI: 0.93-1.75) and transport activity (high vs. retirement, OR: 1.05, 95% CI: 0.69-1.60) were not associated with OSA risk after considering potential confounders. Any specific component of LTPA and two LTPA patterns were also not associated with OSA risk. Stratified analysis yielded similar nonsignificant association of OSA risk with three dimensions of physical activity in both the retirement group and non-retirement group.

CONCLUSION

This study found that three dimensions of physical activity, including LTPA, transport activity, and occupational activity, were not associated with any risk of OSA. Future studies with longitudinal design are needed.

摘要

目的

本研究旨在调查中国成年人身体活动与阻塞性睡眠呼吸暂停(OSA)风险之间的关联。

方法

参与者选自广州心脏研究的基线调查。通过使用柏林问卷确定OSA,并使用改良的全球身体活动问卷测量身体活动,包括休闲时间身体活动(LTPA)、职业活动和交通活动。采用主成分分析提取LTPA模式并进行方差最大化正交变换。使用逻辑回归方法计算95%置信区间(95%CI)的比值比(OR)。

结果

对于所有9733名年龄在35至74岁的参与者,在考虑潜在混杂因素后,LTPA(高活动量与不活动,OR:0.81,95%CI:0.64 - 1.03)、职业活动(高强度与退休,OR:1.28,95%CI:0.93 - 1.75)和交通活动(高活动量与退休,OR:1.05,95%CI:0.69 - 1.60)与OSA风险均无关联。LTPA的任何特定成分以及两种LTPA模式也与OSA风险无关。分层分析显示,退休组和非退休组中,OSA风险与身体活动的三个维度之间均存在类似的无显著关联。

结论

本研究发现,包括LTPA、交通活动和职业活动在内的身体活动的三个维度与OSA的任何风险均无关联。需要开展具有纵向设计的未来研究。

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