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与人类免疫缺陷病毒感染相关的亚急性结构性肌病

Subacute structural myopathy associated with human immunodeficiency virus infection.

作者信息

Gonzales M F, Olney R K, So Y T, Greco C M, McQuinn B A, Miller R G, DeArmond S J

机构信息

Department of Pathology, University of California, San Francisco 94143.

出版信息

Arch Neurol. 1988 May;45(5):585-7. doi: 10.1001/archneur.1988.00520290125026.

Abstract

An unusual myopathy characterized by selective loss of thick filaments and widespread formation of rod bodies is described in two men, both seropositive for human immunodeficiency virus. We were unable to find any previous reports documenting this combination of morphological abnormalities, which we believe may be related to human immunodeficiency virus infection. Both patients responded to treatment: one, to steroid therapy; the other, to plasmapheresis.

摘要

两名血清学检测显示人类免疫缺陷病毒呈阳性的男性被诊断出患有一种罕见的肌病,其特征为粗肌丝选择性缺失以及广泛的杆状体形成。我们未能找到之前有文献记录这种形态学异常组合的报告,我们认为这可能与人类免疫缺陷病毒感染有关。两名患者对治疗均有反应:一名患者对类固醇疗法有反应,另一名患者对血浆置换有反应。

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