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评估中性粒细胞与淋巴细胞比值对克里米亚-刚果出血热预后的预测价值。

Evaluation of neutrophil to lymphocyte ratio in predicting the prognosis of Crimean-Congo haemorrhagic fever.

机构信息

Faculty of Medicine, Ondokuz Mayis University, Infectious Diseases and Clinical Microbiology, Samsun, Turkey.

出版信息

Trop Doct. 2021 Apr;51(2):155-157. doi: 10.1177/0049475521993703. Epub 2021 Feb 15.

DOI:10.1177/0049475521993703
PMID:33588702
Abstract

Crimean-Congo haemorrhagic fever (CCHF) is a severe form of haemorrhagic fever identified in parts of Africa, Asia, Eastern Europe and the Middle East. CCHF continues to be a justifiable cause of concern for people in rural areas where the disease is endemic. A total of 151 patients, diagnosed with CCHF, were evaluated retrospectively. The demographic characteristics of these patients and the relationship between the neutrophil-lymphocyte ratio (NLR) at admission and survival were examined. There were 21 (13.9%) deaths. There was no relationship between age, gender and mortality, but elevated neutrophil-lymphocyte ratio (NLR) on admission was statistically associated with mortality. NLR is a laboratory marker that can be studied even in medical centres with limited facilities and may be helpful in predicting the clinical course of the disease.

摘要

克里米亚-刚果出血热(CCHF)是一种在非洲、亚洲、东欧和中东部分地区发现的严重出血热形式。该病在疾病流行的农村地区仍然是人们合理关注的原因。共有 151 名被诊断患有 CCHF 的患者接受了回顾性评估。检查了这些患者的人口统计学特征以及入院时中性粒细胞-淋巴细胞比值(NLR)与存活率之间的关系。有 21 例(13.9%)死亡。年龄、性别与死亡率之间没有关系,但是入院时升高的中性粒细胞-淋巴细胞比值(NLR)与死亡率具有统计学相关性。NLR 是一种实验室标志物,即使在设施有限的医学中心也可以进行研究,并且可能有助于预测疾病的临床过程。

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