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诊断病例：非典型性 Grover 病。

Case for diagnosis. Atypical Grover's disease.

机构信息

Department of Dermatology, Faculty of Medicine, Universidad de Chile, Santiago, Chile.

Department of Dermatology, Faculty of Medicine, Universidad de Chile, Santiago, Chile.

出版信息

An Bras Dermatol. 2021 Mar-Apr;96(2):234-236. doi: 10.1016/j.abd.2020.06.011. Epub 2021 Feb 2.

DOI:10.1016/j.abd.2020.06.011
PMID:33589293
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8007481/
Abstract

A 55-year-old male presented with an eight-month history of erythematous papules and plaques with demarcated areas of spared skin on his trunk, upper extremities, neck, and face. Grover's disease is a rare, acquired disorder of unknown origin, which is classically characterized by the appearance of erythematous papules on the upper trunk that are usually transient. As in the present case, there are reports of atypical disease, with facial involvement, pityriasis rubra pilaris-like lesions, and a more chronic course.

摘要

一位 55 岁男性，因躯干部、上肢、颈部和面部出现红斑丘疹和界限分明的皮肤脱色斑，前来就诊。Grover 病是一种罕见的、原因不明的获得性疾病，其特征性表现为上躯干出现红斑性丘疹，通常为一过性。与本例一样，也有报道称该病存在非典型表现，包括面部受累、毛发红糠疹样皮损和更慢性病程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14ec/8007481/6665cac1629e/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14ec/8007481/613318b09b28/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14ec/8007481/8f07304bc417/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14ec/8007481/d65040390a77/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14ec/8007481/6665cac1629e/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14ec/8007481/613318b09b28/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14ec/8007481/8f07304bc417/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14ec/8007481/d65040390a77/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14ec/8007481/6665cac1629e/gr4.jpg

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引用本文的文献

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J Dtsch Dermatol Ges. 2025 Feb;23(2):231-233. doi: 10.1111/ddg.15597. Epub 2024 Nov 27.

本文引用的文献

1
Grover disease: review of subtypes with a focus on management options.格罗弗病：各亚型综述，重点介绍治疗选择。
Int J Dermatol. 2020 May;59(5):543-550. doi: 10.1111/ijd.14700. Epub 2019 Nov 14.
2
Pityriasis rubra pilaris-like eruption in the setting of transient acantholytic dermatosis.短暂性棘层松解性皮病背景下的毛发红糠疹样皮疹。
JAAD Case Rep. 2019 Aug 5;5(8):733-735. doi: 10.1016/j.jdcr.2019.06.025. eCollection 2019 Aug.
3
Atypical features and systemic associations in extensive cases of Grover disease: A systematic review.
广泛型 Grover 病的非典型特征及全身相关性：系统综述。
J Am Acad Dermatol. 2017 Nov;77(5):952-957.e1. doi: 10.1016/j.jaad.2017.06.041. Epub 2017 Sep 14.
4
Pseudoherpetic transient acantholytic dermatosis (Grover disease): case series and review of the literature.假疱疹样暂时性棘层松解性皮病（格罗弗病）：病例系列及文献综述
J Cutan Pathol. 2017 May;44(5):486-489. doi: 10.1111/cup.12909. Epub 2017 Feb 16.
5
Dermoscopy of Grover disease.格罗弗病的皮肤镜检查
J Am Acad Dermatol. 2017 Feb;76(2S1):S60-S63. doi: 10.1016/j.jaad.2016.07.031.
6
Dermoscopy of Grover's disease: Variability according to histological subtype.格罗弗病的皮肤镜检查：根据组织学亚型的变异性
J Dermatol. 2016 Aug;43(8):937-9. doi: 10.1111/1346-8138.13298. Epub 2016 Feb 19.
7
Grover disease: a reappraisal of histopathological diagnostic criteria in 120 cases.格罗弗病：120例组织病理学诊断标准的重新评估
Am J Dermatopathol. 2010 Aug;32(6):541-9. doi: 10.1097/DAD.0b013e3181c80cf9.
8
Grover disease (transient acantholytic dermatosis).格罗弗病（暂时性棘层松解性皮肤病）。
Arch Pathol Lab Med. 2009 Sep;133(9):1490-4. doi: 10.5858/133.9.1490.
9
Grover's disease: 34 years on.格罗弗病：34年回顾
Australas J Dermatol. 2004 May;45(2):83-6; quiz 87-8. doi: 10.1111/j.1440-0960.2004.054_1.x.