Kuo Po-Chih, Tsai Cheng Che, López Diego M, Karargyris Alexandros, Pollard Tom J, Johnson Alistair E W, Celi Leo Anthony
Laboratory for Computational Physiology, Massachusetts Institute of Technology, Cambridge, MA, USA.
Department of Computer Science, National Tsing Hua University, Hsinchu, Taiwan.
NPJ Digit Med. 2021 Feb 15;4(1):25. doi: 10.1038/s41746-021-00393-9.
Image-based teleconsultation using smartphones has become increasingly popular. In parallel, deep learning algorithms have been developed to detect radiological findings in chest X-rays (CXRs). However, the feasibility of using smartphones to automate this process has yet to be evaluated. This study developed a recalibration method to build deep learning models to detect radiological findings on CXR photographs. Two publicly available databases (MIMIC-CXR and CheXpert) were used to build the models, and four derivative datasets containing 6453 CXR photographs were collected to evaluate model performance. After recalibration, the model achieved areas under the receiver operating characteristic curve of 0.80 (95% confidence interval: 0.78-0.82), 0.88 (0.86-0.90), 0.81 (0.79-0.84), 0.79 (0.77-0.81), 0.84 (0.80-0.88), and 0.90 (0.88-0.92), respectively, for detecting cardiomegaly, edema, consolidation, atelectasis, pneumothorax, and pleural effusion. The recalibration strategy, respectively, recovered 84.9%, 83.5%, 53.2%, 57.8%, 69.9%, and 83.0% of performance losses of the uncalibrated model. We conclude that the recalibration method can transfer models from digital CXRs to CXR photographs, which is expected to help physicians' clinical works.
使用智能手机进行基于图像的远程会诊越来越受欢迎。与此同时,已开发出深度学习算法来检测胸部X光片(CXR)中的放射学表现。然而,使用智能手机自动执行此过程的可行性尚未得到评估。本研究开发了一种重新校准方法,以构建用于检测CXR照片中放射学表现的深度学习模型。使用两个公开可用的数据库(MIMIC-CXR和CheXpert)构建模型,并收集了四个包含6453张CXR照片的衍生数据集来评估模型性能。重新校准后,该模型在检测心脏肥大、水肿、实变、肺不张、气胸和胸腔积液时,受试者操作特征曲线下面积分别为0.80(95%置信区间:0.78-0.82)、0.88(0.86-0.90)、0.81(0.79-0.84)、0.79(0.77-0.81)、0.84(0.80-0.88)和0.90(0.88-0.92)。重新校准策略分别挽回了未校准模型84.9%、83.5%、53.2%、57.8%、69.9%和83.0%的性能损失。我们得出结论,重新校准方法可以将模型从数字CXR转换为CXR照片,有望帮助医生开展临床工作。