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利用计算机图像处理技术对大鼠梨状皮质中2-脱氧葡萄糖摄取进行代谢图谱分析。

Metabolic mapping of 2-deoxyglucose uptake in the rat piriform cortex using computerized image processing.

作者信息

Cattarelli M, Astic L, Kauer J S

机构信息

Physiologie Neurosensorielle, Université Claude-Bernard, Villeurbanne, France.

出版信息

Brain Res. 1988 Feb 23;442(1):180-4. doi: 10.1016/0006-8993(88)91449-7.

DOI:10.1016/0006-8993(88)91449-7
PMID:3359252
Abstract

Using a computerized image processing method, the metabolic activity of the unfolded molecular and pyramidal layers of the piriform cortex was studied in rats during odorous stimulation. Animals were either intact or had sustained a bilateral transection of the lateral olfactory tract. 2-DG labelling was observed in corresponding areas across these two layers. No spatial pattern of 2-DG uptake could be seen in correlation with the odorant quality. These results are discussed with respect to the known anatomical and functional properties of the piriform cortex.

摘要

采用计算机图像处理方法,研究了大鼠在嗅觉刺激过程中梨状皮质未折叠分子层和锥体细胞层的代谢活性。实验动物分为完整组和双侧嗅束横断组。在这两层相应区域观察到2-脱氧葡萄糖(2-DG)标记。未发现2-DG摄取的空间模式与气味质量相关。结合梨状皮质已知的解剖学和功能特性对这些结果进行了讨论。

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