Rodilla V, Pertusa J, Pellicer J A
Department of Animal Biology, University of Valencia, Spain.
Cancer Lett. 1988 Mar;39(2):179-83. doi: 10.1016/0304-3835(88)90102-4.
The incorporation of cis-diammine Dichloro Platinum (II) (cisplatin) on the Ehrlich ascites carcinoma (EAT) cells has been studied in this paper. Ultrastructural study of cells treated 'in vivo' with cisplatin showed that a new treatment with this substance after fixation, blocks uranyl acetate staining with the consequent lack of heterochromatin contrast.
本文研究了顺二氯二氨合铂（II）（顺铂）在艾氏腹水癌（EAT）细胞中的掺入情况。对经顺铂“体内”处理的细胞进行超微结构研究表明，固定后用该物质进行新的处理会阻止醋酸铀染色，从而导致异染色质对比度缺失。
