与COVID-19相关的播散性感染。

Alegre-González Diana, Herrera Sabina, Bernal Javier, Soriano Alex, Bodro Marta

Department of Internal Medicine, Hospital San Pedro, Logroño, 26007, Spain.

Department of Infectious Diseases, Hospital Clinic, Barcelona, 08036, Spain.

Med Mycol Case Rep. 2021 Dec;34:35-37. doi: 10.1016/j.mmcr.2021.10.001. Epub 2021 Oct 22.

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a novel coronavirus associated with immune dysregulation. The use of immunosuppressant drugs as part of COVID-19 treatment (such as Tocilizumab or high -dose corticosteroids) increases the risk of opportunistic infections. Here we present a case of a patient without prior immunosuppression that developed a serious fungal infection after the use of high dose corticosteroids in the setting of severe COVID-19 and cryptogenic organizing pneumonia.

严重急性呼吸综合征冠状病毒2（SARS-CoV-2）是一种与免疫失调相关的新型冠状病毒。使用免疫抑制药物作为COVID-19治疗的一部分（如托珠单抗或高剂量皮质类固醇）会增加机会性感染的风险。在此，我们报告一例在严重COVID-19和隐源性机化性肺炎背景下使用高剂量皮质类固醇后发生严重真菌感染的患者，该患者既往无免疫抑制情况。