Australia Nuclear Science and Technology Organization, Lucas Heights, New South Wales 2234, Australia.
Monash Biomedical Imaging, Monash University, Melbourne, Victoria 3800, Australia.
Magn Reson Imaging. 2021 Jun;79:112-120. doi: 10.1016/j.mri.2021.02.010. Epub 2021 Feb 15.
We report the design, construction, and initial tests of a hyperpolariser to produce polarised Xe and He gas for medical imaging of the lung. The hyperpolariser uses the Spin-Exchange Optical Pumping method to polarise the nuclear spins of the isotopic gas. Batch mode operation was chosen for the design to produce polarised Xe and polarised He. Two-side pumping, electrical heating and a piston to transfer the polarised gas were some of the implemented techniques that are not commonly used in hyperpolariser designs. We have carried out magnetic resonance imaging experiments demonstrating that the He and Xe polarisation reached were sufficient for imaging, in particular for in vivo lung imaging using Xe. Further improvements to the hyperpolariser have also been discussed.
我们报告了一种用于产生极化氙气和氦气的极化器的设计、构建和初步测试，该极化器用于肺部医学成像。该极化器使用自旋交换光学泵浦方法来极化同位素气体的核自旋。设计采用批量模式操作来产生极化氙气和极化氦气。双侧泵浦、电加热和用于转移极化气体的活塞是一些在极化器设计中不常用的技术。我们已经进行了磁共振成像实验，证明达到的氦气和氙气极化度足以进行成像，特别是使用氙气进行体内肺部成像。还讨论了对极化器的进一步改进。
