Department of Oral Medicine, School of Dentistry, Arak University of Medical Sciences, Arak, Iran.
School of Dentistry, Arak University of Medical Sciences, Arak, Iran.
BMC Oral Health. 2021 Feb 18;21(1):77. doi: 10.1186/s12903-021-01434-1.
The effect of low-level laser therapy (LLLT) on pain mitigation following the third molar surgery is still controversial. The absence of a standard method for using laser among the studies is related to the types of sample selection, sample size, control, and LLLT parameters, which make pain mitigation following surgery more controversial. Therefore, this study aimed to determine the effect of LLLT on reducing pain, swelling, and trismus following the mandibular impacted third molar surgery.
This study was performed on 25 healthy subjects. After the surgery, amoxicillin 500 mg was prescribed every 8 h for a 7-day period besides oral Ibuprofen (Gelofen) 400 mg every 12 h for a 3-day period. The intraoral Laser diode 940 nm was applied immediately after suture on the tested side, while on the placebo side, a fiber tip was used with no laser radiation following surgery. Eventually, the pain score was evaluated by VAS index from the 1st to the 7th-day post-surgery and then analyzed by SPSS 24.
The results indicate that the mean swelling and trismus before, during, 2 days after, and 7 days after the intervention did not differ significantly between the two studied groups. However, the results show that on the sixth and seventh days, the pain was significantly lower in the intervention group compared to the control group.
The results suggest that although the pain, swelling, and trismus following surgery were lower on the radiated side, only pain was found to be significant on the radiated side (p < 0.05). The registration number of the clinical trial in a Primary Registry in the WHO Registry Network is IRCT20141209020258N110 and the date of retrospective registration is 04/05/2019. The related URL is https://www.irct.ir/trial/36321 .
低水平激光疗法（LLLT）对减轻第三磨牙手术后疼痛的效果仍存在争议。研究中缺乏使用激光的标准方法与样本选择、样本量、对照和 LLLT 参数的类型有关，这使得手术后的疼痛缓解问题更加具有争议性。因此，本研究旨在确定 LLLT 对减轻下颌阻生第三磨牙手术后疼痛、肿胀和牙关紧闭的效果。
本研究纳入了 25 名健康受试者。手术后，除了每天 8 小时服用 500 毫克阿莫西林 7 天外，还每天 12 小时口服布洛芬（凝胶）400 毫克 3 天。激光二极管 940nm 立即在缝线部位进行口腔内照射，而在安慰剂侧，使用光纤尖端，手术后无激光辐射。最终，术后第 1 天至第 7 天，通过视觉模拟评分（VAS）指数评估疼痛评分，并使用 SPSS 24 进行分析。
结果表明，两组研究对象在手术前、手术期间、手术后 2 天和手术后 7 天的肿胀和牙关紧闭程度无显著差异。然而，结果显示，在第 6 天和第 7 天，干预组的疼痛明显低于对照组。
结果表明，尽管辐射侧手术后的疼痛、肿胀和牙关紧闭程度较低，但仅在辐射侧发现疼痛具有显著差异（p<0.05）。该临床试验的注册号是 IRCT20141209020258N110，在世界卫生组织注册网络的主要注册中心注册日期是 2019 年 4 月 5 日。相关网址是 https://www.irct.ir/trial/36321。
