Witmanowski Henryk, Błochowiak Katarzyna
Department of Plastic, Reconstructive and Aesthetic Surgery, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Department of Oral Surgery and Periodontology, Poznan University of Medical Sciences, Poznan, Poland.
Postepy Dermatol Alergol. 2020 Dec;37(6):853-861. doi: 10.5114/ada.2019.82795. Epub 2019 Feb 5.
Treatment with botulinum toxin is widely viewed as safe, effective and largely devoid of serious side effects. There are two classes of Botox-related adverse events - transient and benign events, and potentially serious events. The aim of this study was to provide an overview of Botox-related side effects and advise potential management and preventive strategies. Benign side effects are well-localized, reversible and self-limited complications which develop within a few days of the injection, and they usually disappear without any treatment. The aesthetic and functional adverse effects are associated with different muscle responses to botulinum toxin or with misplacement of botulinum toxin. The serious events are sequelae due to the systemic spread of toxin leading to botulism.
肉毒杆菌毒素治疗被广泛认为是安全、有效的，且基本没有严重副作用。与肉毒杆菌毒素相关的不良事件有两类——短暂性和良性事件，以及潜在的严重事件。本研究的目的是概述与肉毒杆菌毒素相关的副作用，并提供潜在的管理和预防策略。良性副作用是定位明确、可逆且自限性的并发症，在注射后几天内出现，通常无需任何治疗即可消失。美学和功能方面的不良反应与肌肉对肉毒杆菌毒素的不同反应或肉毒杆菌毒素的误注射有关。严重事件是由于毒素全身扩散导致肉毒中毒的后遗症。
