Department of Otolaryngology, Cheng Hsin General Hospital, Taipei, Taiwan.
Department of Medical Research and Education, Cheng Hsin General Hospital, Taipei, Taiwan.
PLoS One. 2021 Feb 19;16(2):e0246545. doi: 10.1371/journal.pone.0246545. eCollection 2021.
Cochlear implantation is currently the most effective treatment modality for severe to profound sensorineural hearing loss. Over the past few years, at the Department of Otolaryngology, Cheng Hsin General Hospital (Taipei, Taiwan), cochlear implant devices have been switched on within 24 hours of their implantation. Differences in impedance evolution after early switch-on for different devices have not been previously discussed. The present study aimed to investigate the impedance evolution of one device and the factors influencing this after early activation. Results are compared to published results of other devices. A total of 16 patients who received Advanced BionicsTM devices and had early activation within 24 hours of implantation, were included in the study. Impedance telemetry was recorded intraoperatively and postoperatively at 1 day, 1 week, 2 weeks, 4 weeks and 8 weeks. A stepwise increase was observed in the impedance evolution. To the best of our knowledge, the present study is the first to investigate the impedance evolution of the different devices after early switch-on within 24 hours of implantation and its influencing factors. Further research with a longitudinal design to compare the differences in electrode impedances between patients activated early versus those activated after a few weeks will be necessary for the disclosure of the underlying mechanisms.
人工耳蜗植入术目前是治疗重度至极重度感音神经性听力损失最有效的方法。在过去的几年中，成大医院耳鼻喉部（台湾台北）在人工耳蜗植入术后 24 小时内开机。之前尚未讨论过不同设备早期开机后阻抗演变的差异。本研究旨在探讨一种设备的阻抗演变及其早期激活后影响因素。将结果与其他设备的已发表结果进行比较。本研究共纳入 16 名植入后 24 小时内接受先进仿生公司设备早期激活的患者。术中及术后第 1、1 周、2 周、4 周和 8 周记录阻抗遥测。观察到阻抗逐渐升高。据我们所知，本研究首次探讨了不同设备在植入后 24 小时内早期开机后的阻抗演变及其影响因素。为了揭示潜在的机制，需要进行一项前瞻性设计的研究，以比较早期激活和数周后激活的患者之间电极阻抗的差异。
