Steno Diabetes Center Copenhagen, Niels Steensens Vej 2, Gentofte, DK-2820 Denmark.
Steno Diabetes Center Copenhagen, Niels Steensens Vej 2, Gentofte, DK-2820 Denmark.
Nutr Res. 2021 Mar;87:91-96. doi: 10.1016/j.nutres.2020.12.015. Epub 2020 Dec 24.
Late-evening food intake is associated with cardiometabolic risk. We assessed the prevalence of late-evening and night-time eating in individuals with type 2 diabetes and its association with BMI and HbA. We hypothesized food intake during late evening and night-time to be prevalent among individuals with type 2 diabetes and to be associated with higher BMI and higher HbA. This cross-sectional analysis includes 348 adults with type 2 diabetes from an outpatient diabetes clinic in Denmark. Frequency of late-evening and night-time eating was assessed from a food frequency questionnaire and clinical data were obtained from electronic medical records. Participants were divided into those reporting to eat frequently (≥3 times/week) in the evening after dinner and/or during night-time (late-eaters) and those who did not (reference group) and BMI and HbA levels were compared between groups with and without adjustment for diabetes duration and antidiabetic medication. 42% of the study population reported to eat frequently (≥3 times/week) in the late evening and 8% reported to do so during the night. Most late-eaters reported to eat breakfast regularly, suggesting a long eating window and short fasting period in this group. BMI and HbA did not differ between late-eaters and the reference group. Eating late in the evening or during the night was prevalent among individuals with type 2 diabetes across BMI and HbA levels. Whether restriction of food intake during evening and night-time can induce weight loss and improve glycemic control in individuals with type 2 diabetes needs testing in randomized controlled trials.
深夜进食与心血管代谢风险相关。我们评估了 2 型糖尿病患者深夜和夜间进食的流行情况及其与 BMI 和 HbA 的关系。我们假设 2 型糖尿病患者深夜和夜间进食较为普遍,且与更高的 BMI 和更高的 HbA 相关。这项横断面分析纳入了丹麦一家门诊糖尿病诊所的 348 名 2 型糖尿病患者。通过食物频率问卷评估深夜和夜间进食的频率,从电子病历中获取临床数据。将报告晚餐后和/或夜间频繁(每周≥3 次)进食的参与者分为夜间进食者(晚食者)和不进食者(参照组),并比较两组之间的 BMI 和 HbA 水平,是否调整了糖尿病病程和降糖药物。研究人群中有 42%报告经常(每周≥3 次)在深夜进食,8%报告在夜间进食。大多数晚食者报告规律吃早餐,这表明他们的进食窗口较长,禁食时间较短。晚食者与参照组之间的 BMI 和 HbA 无差异。无论 BMI 和 HbA 水平如何,2 型糖尿病患者深夜进食或夜间进食较为普遍。在 2 型糖尿病患者中,限制夜间和夜间进食是否能诱导体重减轻和改善血糖控制,需要在随机对照试验中进行检验。