Mirghani Hyder
Internal Medicine, University of Tabuk, Tabuk, SAU.
Cureus. 2021 Jun 23;13(6):e15853. doi: 10.7759/cureus.15853. eCollection 2021 Jun.
Introduction There is an increasing awareness regarding the effects of chrono-nutrition on glycemic control and weight regulation. Therefore, this study aimed to determine the relationship between breakfast skipping and late-night eating to body mass index and glycemic control among patients with type 2 diabetes. Subjects and methods This cross-sectional study was conducted among 310 patients with diabetes in Tabuk City, Saudi Arabia during the period from December 2020 to April 2021. A structured questionnaire was used to interview the participants, the following were reported: demographic data, breakfast skipping, late-night eating, smoking, level of exercise, family history of diabetes, and diabetes complications. Weight and height were measured to calculate the body mass index (BMI), and the last glycated hemoglobin was collected to estimate the degree of glycemic control. Statistical Package for Social Sciences (SPSS Statistics, IBM Corp., Armonk, USA) was used for data analysis. The ethical committee of the University of Tabuk approved the research. Results Out of 310 patients with diabetes (54.8% women), nearly half (45.2%) were breakfast-skippers and 20% eat late at night. Breakfast skipping was correlated with BMI (Wald, 5.481, CI, 0.154-0.847, P-value, 0.019). A positive direct correlation was evident between late dinner intake, BMI, and HbA1c (Wald, 4.210, 95% CI 0.743-0.993, P-value, 0.04 for HbA1c, and Wald, 6.777, 95% CI 1.0221-1.165 P-value, 0.009 for BMI). Conclusion Breakfast skipping and late dinner intake were associated with obesity, while only late dinner consumption was associated with poor glycemic control. Further larger multi-center studies investigating the chronotype and glycemic index are recommended.
引言 人们越来越意识到时间营养学对血糖控制和体重调节的影响。因此,本研究旨在确定2型糖尿病患者不吃早餐和晚餐过晚与体重指数和血糖控制之间的关系。
对象与方法 本横断面研究于2020年12月至2021年4月期间在沙特阿拉伯塔布克市的310名糖尿病患者中进行。使用结构化问卷对参与者进行访谈,记录以下信息:人口统计学数据、不吃早餐、晚餐过晚、吸烟、运动水平、糖尿病家族史和糖尿病并发症。测量体重和身高以计算体重指数(BMI),并收集最后一次糖化血红蛋白以评估血糖控制程度。使用社会科学统计软件包(SPSS Statistics,美国国际商业机器公司,纽约州阿蒙克)进行数据分析。塔布克大学伦理委员会批准了该研究。
结果 在310名糖尿病患者中(54.8%为女性),近一半(45.2%)不吃早餐,20%晚餐过晚。不吃早餐与BMI相关(Wald值为5.481,置信区间为0.154 - 0.847,P值为0.019)。晚餐摄入过晚、BMI和糖化血红蛋白之间存在明显的正相关(糖化血红蛋白的Wald值为4.210,95%置信区间为0.743 - 0.993,P值为0.04;BMI的Wald值为6.777,95%置信区间为1.0221 - 1.165,P值为0.009)。
结论 不吃早餐和晚餐过晚与肥胖有关,而只有晚餐过晚与血糖控制不佳有关。建议进一步开展更大规模的多中心研究,调查生物钟类型和血糖指数。