Department of Dentistry Avenida Governador Marcelo Deda, 300 Postal Code 49400-000. São José Lizard, Lagarto (SE). Brazil
Med Oral Patol Oral Cir Bucal. 2021 Mar 1;26(2):e216-e225. doi: 10.4317/medoral.24144.
Primary burning mouth syndrome (BMS) is a chronic clinical condition of idiopathic mainly characterized by pain and a burning sensation in the oral cavity. The application of laser at low intensity therapy is a treatment option. This systematic review evaluated the efficacy of laser therapy in treating symptoms of burning mouth syndrome.
The study was formulated according to the PRISMA and Cochrane guidelines. Seven databases were used as primary sources of research. Only randomized controlled clinical trials were included. The efficacy of the therapy was estimated comparing the values of the visual and numerical scales of pain before and after laser treatment, through qualitative analysis.
The search resulted in 348 records and only eight filled the eligibility criteria and were included. All studies evaluated pain and / or a burning sensation considering a time interval of two to ten weeks. The total sample consisted of 314 patients submitted to treatment: 123 from the control group, who participated with laser off or with the tip blocked, and 191 from the intervention group, treated with low-level laser therapy. The female gender stood out and the average age of the participants was 60.89 years. The main symptoms reported were pain and a burning sensation in the oral mucosa and tongue. The parameters adopted by the authors for laser treatment were diverse and the variables were not fully described in the published studies. Visual analog and numerical scales were used to assess symptoms and only three studies showed statistical significance.
It is suggested that laser therapy may be an effective alternative in the treatment of BMS. New randomized clinical trials should consider well-established protocols to better understand the efficacy of laser therapy without confounding the effects.
原发性灼口综合征（BMS）是一种主要表现为口腔疼痛和烧灼感的慢性临床病症。低强度激光治疗是一种治疗选择。本系统评价评估了激光治疗灼口综合征症状的疗效。
该研究根据 PRISMA 和 Cochrane 指南制定。使用了七个数据库作为研究的主要来源。仅纳入随机对照临床试验。通过定性分析，比较激光治疗前后视觉和数字疼痛量表的值来评估治疗效果。
搜索结果产生了 348 条记录，只有 8 条符合纳入标准并被纳入。所有研究均评估了疼痛和/或烧灼感，考虑到两到十周的时间间隔。总样本由 314 名接受治疗的患者组成：对照组 123 名，接受激光关闭或尖端阻塞治疗，干预组 191 名，接受低水平激光治疗。女性占主导地位，参与者的平均年龄为 60.89 岁。报告的主要症状是口腔黏膜和舌部的疼痛和烧灼感。作者采用的激光治疗参数多种多样，发表的研究中没有充分描述变量。视觉模拟和数字量表用于评估症状，只有三项研究显示具有统计学意义。
激光治疗可能是 BMS 治疗的有效选择。新的随机临床试验应考虑既定方案，以更好地了解激光治疗的疗效，而不会混淆疗效。
