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低水平激光疗法的光生物调节对灼口综合征的影响:一项随机临床试验。

Effects of photobiomodulation with low-level laser therapy in burning mouth syndrome: A randomized clinical trial.

机构信息

Department of Dental Clinical Specialties, ORALMED Research Group, School of Dentistry, Complutense University, Madrid, Spain.

出版信息

Oral Dis. 2020 Nov;26(8):1764-1776. doi: 10.1111/odi.13443. Epub 2020 Jun 24.

DOI:10.1111/odi.13443
PMID:32460396
Abstract

BACKGROUND

Photobiomodulation (PBM) has proven to be effective in different painful conditions.

OBJECTIVES

To assess the effect of photobiomodulation for pain management in burning mouth syndrome (BMS) patients, besides analysing the impact on different aspects of quality of life.

METHODS

A randomized, single-blind, clinical trial was performed among 20 patients with BMS. Photobiomodulation was applied in the study group (n = 10) with a dose of 12 J/cm during 10 sessions, comparing with a placebo group (n = 10) with the laser turned off. Pain was assessed using the visual analogue scale (VAS) before starting each treatment session, and at the 1-month and 4-month follow-up appointments. Some validated questionnaires for general health were also complete: SF-36, OHIP-14, Epworth, SCL 90-R and McGill.

RESULTS

All patients (n = 10) in the study group improved their pain ending treatment and remaining among 90% (n = 9) in the 4-month follow-up. Significant improvement was found in the study group in some sections of McGill questionnaire, Epworth scale, and SCL 90-R at the end of the treatment and in the 1-month and 4-month follow-ups.

CONCLUSIONS

Photobiomodulation seems to be effective in reducing pain in patients with BMS, as well as, having a positive impact on the psychological state of these patients.

摘要

背景

光生物调节(PBM)已被证明在各种疼痛病症中有效。

目的

评估光生物调节对灼口综合征(BMS)患者疼痛管理的效果,同时分析其对生活质量不同方面的影响。

方法

对 20 名 BMS 患者进行了一项随机、单盲、临床试验。研究组(n=10)接受 12 J/cm 的剂量,共进行 10 次光生物调节治疗,而对照组(n=10)则使用关闭激光的安慰剂。在每次治疗前、治疗结束后 1 个月和 4 个月随访时,使用视觉模拟量表(VAS)评估疼痛。还完成了一些针对一般健康的经过验证的问卷:SF-36、OHIP-14、Epworth、SCL 90-R 和 McGill。

结果

研究组所有患者(n=10)在治疗结束时疼痛均有所改善,其中 90%(n=9)在 4 个月随访时仍有改善。在治疗结束时以及治疗结束后 1 个月和 4 个月随访时,研究组在 McGill 问卷的一些部分、Epworth 量表和 SCL 90-R 中的评分显著改善。

结论

光生物调节似乎可有效减轻 BMS 患者的疼痛,同时对这些患者的心理状态产生积极影响。

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