中性粒细胞与白蛋白比值作为乙型肝炎相关性失代偿性肝硬化的预后指标。
Neutrophil count to albumin ratio as a prognostic indicator for HBV-associated decompensated cirrhosis.
机构信息
Department of Clinical Laboratory, Shengzhou People's Hospital, Shengzhou Branch of the First Affiliated Hospital of Zhejiang University, Shengzhou, China.
出版信息
J Clin Lab Anal. 2021 Apr;35(4):e23730. doi: 10.1002/jcla.23730. Epub 2021 Feb 20.
Abstract
BACKGROUND
To explore the value of neutrophil count to albumin ratio (NAR) in predicting the outcomes of patients with HBV-associated decompensated cirrhosis (HBV-DeCi).
METHODS
One hundred and fifty-four HBV-DeCi patients were enrolled. The 30-day mortality was determined. Multivariate analysis was applied to identify risk factors for poor outcomes. Receiver operating characteristic curve analyses was performed to evaluate prognostic accuracy.
RESULTS
The 30-day mortality was 10.4%. NAR was significantly higher in non-survivors than in survivors and was an independent predictor for unfavorable prognosis.
CONCLUSIONS
The present results indicate that increased NAR is associated with poor survival in HBV-DeCi patients and has potential for clinical application.
摘要
背景
探讨中性粒细胞与白蛋白比值（NAR）预测乙型肝炎相关失代偿性肝硬化（HBV-DeCi）患者结局的价值。
方法
纳入 154 例 HBV-DeCi 患者，确定 30 天死亡率。采用多因素分析确定不良结局的危险因素。进行受试者工作特征曲线分析评估预后准确性。
结果
30 天死亡率为 10.4%。非幸存者的 NAR 显著高于幸存者，是不良预后的独立预测因子。
结论
本研究结果表明，HBV-DeCi 患者 NAR 升高与生存不良相关，具有临床应用潜力。
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