Department of Agriculture, Forestry and Bioresources, Plant Genomics and Breeding Institute, Research Institute of Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Korea.
Department of Chemistry and Life Science, Bioscience Institute, Sahmyook University, Seoul, 01795, Republic of Korea.
Genes Genomics. 2021 Mar;43(3):209-215. doi: 10.1007/s13258-021-01047-6. Epub 2021 Feb 20.
Panax ginseng is one of the most valuable medicinal plants in Korea. However, deciphering its full genome sequence information for crop improvement has been hampered due to its complex genomic, genetic, and growth characteristics. Many efforts have been made in the past decade to overcome these limitations and understand the genome structure and the evolutionary history of P. ginseng.
This review aims to discuss the current status of genomic studies on P. ginseng and related species, and the experimental clues suggesting phylogenetic classification and evolutionary history of the genus Panax.
The development of sequencing technologies made genome sequencing of the large P. ginseng genome possible, providing fundamental information to deciphering the evolutionary history of P. ginseng and related species. P. ginseng went through two rounds of whole genome duplication events after diverging from the closest family Apiaceae, which was unveiled from complete whole genome sequences. Further in-depth comparative genome analysis with other related species and genera will uncover the evolutionary history as well as important morphological and ecological characteristics of Panax species.
人参是韩国最有价值的药用植物之一。然而，由于其复杂的基因组、遗传和生长特性，破译其全基因组序列信息以用于作物改良一直受到阻碍。过去十年中，人们做出了许多努力来克服这些限制，以了解人参的基因组结构和进化历史。
本综述旨在讨论人参及相关物种的基因组研究现状，以及实验线索表明的属人参的系统发生分类和进化历史。
测序技术的发展使得大型人参基因组的测序成为可能，为破译人参及相关物种的进化历史提供了基础信息。人参在与最接近的伞形科家族分化后经历了两轮全基因组复制事件，这是从完整的全基因组序列中揭示出来的。进一步与其他相关物种和属进行深入的比较基因组分析，将揭示人参属的进化历史以及重要的形态和生态特征。
