Kolar O J, Burkhart J E
Br J Vener Dis. 1977 Aug;53(4):221-5. doi: 10.1136/sti.53.4.221.
In patients with abnormal neuropsychiatric symptoms and a reactive fluorescent treponemal antibody absoption (FTA-ABS) test in the cerebrospinal fluid (CSF) or serum, a normal CSF cell count and total protein concentration does not exlude late syphilis involving the central nervous system. In these patients, the presence of plasma cells in the CSF cytogram, increased concentration of CSF immunoglobulin G (IgG), immunoelectrophoretic abnormalities in the precipitates of the IgG and of the Fab fragments of IgG in the CSF immunoelectropherogram, and an increased serum level of immunoglobulin M (IgM) suggest an active, potentially treatable neurosyphilis.
对于有异常神经精神症状且脑脊液（CSF）或血清中梅毒螺旋体荧光抗体吸收试验（FTA - ABS）呈阳性的患者，脑脊液细胞计数和总蛋白浓度正常并不能排除累及中枢神经系统的晚期梅毒。在这些患者中，脑脊液细胞涂片中有浆细胞、脑脊液免疫球蛋白G（IgG）浓度升高、脑脊液免疫电泳图中IgG沉淀及IgG Fab片段的免疫电泳异常，以及血清免疫球蛋白M（IgM）水平升高，提示存在活动性、可能可治疗的神经梅毒。
