神经梅毒中的脑脊液免疫球蛋白
Cerebrospinal fluid immunoglobulins in neurosyphilis.
作者信息
Gschnait F, Schmidt B L, Luger A
出版信息
Br J Vener Dis. 1981 Aug;57(4):238-40. doi: 10.1136/sti.57.4.238.
Abstract
Using the fluorescent treponemal antibody-absorption (FTA-ABS) test and the solid phase haemadsorption assay (SPHA) Treponema pallidum-specific IgA was found in the cerebrospinal fluid (CSF) of patients with neurosyphilis but not in those with late latent syphilis. The presence of T pallidum-specific IgA in the CSF may inhibit the antitreponemal activity of IgG and thus play some part in the pathogenesis of neurosyphilis.
摘要
运用荧光密螺旋体抗体吸收试验（FTA-ABS）和固相血细胞吸附试验（SPHA），发现神经梅毒患者的脑脊液（CSF）中存在梅毒螺旋体特异性IgA，而晚期潜伏梅毒患者的脑脊液中则未发现。脑脊液中梅毒螺旋体特异性IgA的存在可能会抑制IgG的抗梅毒螺旋体活性，从而在神经梅毒的发病机制中发挥一定作用。
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引用本文的文献
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Diagnosis of neurosyphilis by examination of the cerebrospinal fluid.通过脑脊液检查诊断神经梅毒。
Br J Vener Dis. 1981 Aug;57(4):232-7. doi: 10.1136/sti.57.4.232.
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