Vajhadin Fereshteh, Mazloum-Ardakani Mohammad, Amini Abbas
Department of Chemistry Faculty of Science Yazd University Yazd Iran.
Department of Mechanical Engineering Australian College of Kuwait Safat Kuwait.
Med Devices Sens. 2021 Feb;4(1):e10161. doi: 10.1002/mds3.10161. Epub 2021 Mar 29.
Exhaled breath test is a typical disease monitoring method for replacing blood and urine samples that may create discomfort for patients. To monitor exhaled breath markers, gas biomedical sensors have undergone rapid progress for non-invasive and point-of-care diagnostic devices. Among gas sensors, metal oxide-based biomedical gas sensors have received remarkable attention owing to their unique properties, such as high sensitivity, simple fabrication, miniaturization, portability and real-time monitoring. Herein, we reviewed the recent advances in chemoresistive metal oxide-based gas sensors with ZnO, SnO and InO as sensing materials for monitoring a range of exhaled breath markers (i.e., NO, H, HS, acetone, isoprene and formaldehyde). We focused on the strategies that improve the sensitivity and selectivity of metal oxide-based gas sensors. The challenges to fabricate a functional gas sensor with high sensing performance along with suggestions are outlined.
呼气测试是一种典型的疾病监测方法，用于替代可能给患者带来不适的血液和尿液样本。为了监测呼气标志物，气体生物医学传感器在非侵入性和即时诊断设备方面取得了快速进展。在气体传感器中，基于金属氧化物的生物医学气体传感器因其独特的性能，如高灵敏度、简单制造、小型化、便携性和实时监测，而受到了显著关注。在此，我们综述了以ZnO、SnO和InO为传感材料的基于化学电阻的金属氧化物气体传感器在监测一系列呼气标志物（即NO、H、HS、丙酮、异戊二烯和甲醛）方面的最新进展。我们重点关注了提高基于金属氧化物的气体传感器灵敏度和选择性的策略。概述了制造具有高传感性能的功能性气体传感器所面临的挑战以及相关建议。
