Centre for Sexuality and Health Research and Policy (C-SHaRP), Chennai, India.
The Humsafar Trust, Mumbai, India.
AIDS Care. 2022 Mar;34(3):301-309. doi: 10.1080/09540121.2021.1887801. Epub 2021 Feb 21.
HIV pre-exposure prophylaxis (PrEP) is not yet included in India's national AIDS program, with demonstration projects for MSM in planning stages. In order to support PrEP roll-out for MSM, we assessed: (1) associations between guideline-informed PrEP eligibility, HIV risk perception, and perceived PrEP benefits and costs, with willingness to use PrEP (WTUP); and (2) correlates of non-WTUP among PrEP-eligible MSM. Data were collected from MSM ( = 197) sampled from cruising sites in Mumbai and Chennai. More than half (58.4%) reported inconsistent condom use with male partners, 88.3% >1 male partner, and 48.6% engaging in sex work (all past month). Overall, 76.6% reported they would "definitely use" PrEP. Among 92.9% deemed PrEP-eligible, 79.2% reported WTUP. In adjusted analyses, PrEP eligibility (aOR = 5.31, 95% CI 1.11, 25.45), medium (aOR = 2.41, 95% CI 1.03, 5.63) or high (aOR = 13.08, 95% CI 1.29, 132.27) perceived HIV risk, and greater perceived benefits (aOR = 1.13, 95% CI 1.03, 1.24) were associated with higher odds of WTUP. Among PrEP-eligible MSM, non-WTUP was associated with low HIV risk perception and lower perceived benefits. Facilitating accurate risk assessment and promoting awareness of PrEP benefits and eligibility criteria may increase PrEP uptake among MSM in India.
艾滋病毒暴露前预防 (PrEP) 尚未纳入印度国家艾滋病计划，男男性行为者 (MSM) 的示范项目仍处于规划阶段。为了支持 MSM 中 PrEP 的推出，我们评估了：(1) 指南指导的 PrEP 资格、艾滋病毒风险认知以及对 PrEP 益处和成本的认知与使用 PrEP 的意愿 (WTUP) 之间的关联；以及 (2) 符合 PrEP 条件的 MSM 中不使用 WTUP 的相关因素。数据来自从孟买和钦奈的巡游点抽样的 MSM（ = 197）。超过一半（58.4%）报告与男性伴侣的性行为中不经常使用安全套，88.3%有 >1 名男性伴侣，48.6%从事性工作（均为过去一个月）。总体而言，76.6%表示他们“肯定会使用”PrEP。在被认为有资格接受 PrEP 的 92.9%中，79.2%表示 WTUP。在调整后的分析中，PrEP 资格（aOR = 5.31，95%CI 1.11, 25.45）、中等（aOR = 2.41，95%CI 1.03, 5.63）或高（aOR = 13.08，95%CI 1.29, 132.27）的感知艾滋病毒风险以及更高的感知益处（aOR = 1.13，95%CI 1.03, 1.24）与更高的 WTUP 几率相关。在有资格接受 PrEP 的 MSM 中，WTUP 与低艾滋病毒风险认知和较低的感知益处相关。促进准确的风险评估并提高对 PrEP 益处和资格标准的认识，可能会增加印度 MSM 对 PrEP 的接受度。
