Department of Radiology, Complejo Asistencial de Segovia, C/Luis Erik Clavería Neurólogo, s/n, 40002, Segovia, Spain.
Department of Ophthalmology, Complejo Asistencial de Segovia, Segovia, Spain.
Int Ophthalmol. 2021 May;41(5):1863-1874. doi: 10.1007/s10792-021-01748-7. Epub 2021 Feb 23.
To evaluate the reliability and agreement between Fully Refocused Steady-State magnetic resonance sequences (FRSS) and the IOLMaster 500 optical biometer for measuring anterior chamber depth (ACD) and axial length (AL).
In a sample of 32 healthy volunteers, separate observers measured the ACD and AL of both eyes using both techniques (inter-method) and through repeated FRSS measurements (interobserver) and by the same observer (intraobserver). We employed the Bland-Altman method to determine the agreement between FRSS and partial coherence interferometry (using the IOLMaster) and the interobserver and intraobserver variability, providing the limits of agreement (LoA, or mean difference ± 1.96 SD). Correlation coefficients and intraclass correlation coefficients were also provided.
For ACD measurements with FRSS in pseudo-color scale, we obtained an LoA of 0.016 ± 0.266 mm compared with partial coherence interferometry. For AL with FRSS in greyscale, the LoA was 0.019 ± 0.383 mm. Maximum interobserver variability showed a - 0.036 ± 0.247 mm LoA for ACD with FRSS in pseudo-color scale. Maximum intraobserver variability was 0.000 ± 0.157 mm LoA for AL with FRSS in greyscale.
ACD and AL measurements using FRSS sequencing present high LoA and reliability when compared with partial coherence interferometry using the IOLMaster 500. The results were better for FRSS in pseudo-color scale in ACD determination and for FRSS in greyscale in AL determination. FRSS would not be recommended for IOL power calculation due to variability of AL measurement.
评估完全重聚焦稳态磁共振序列（FRSS）与 IOLMaster 500 光学生物测量仪测量前房深度（ACD）和眼轴长度（AL）的可靠性和一致性。
在 32 名健康志愿者的样本中，分别使用两种技术（方法间）和通过重复 FRSS 测量（观察者间）以及同一观察者（观察者内）来测量双眼的 ACD 和 AL。我们采用 Bland-Altman 法来确定 FRSS 与部分相干干涉测量法（使用 IOLMaster）之间的一致性，以及观察者间和观察者内的变异性，提供了一致性界限（LoA，即均值差异 ± 1.96 SD）。还提供了相关系数和组内相关系数。
对于 FRSS 在伪彩色比例尺下测量的 ACD，我们得到的 LoA 为 0.016 ± 0.266 mm，与部分相干干涉测量法相比。对于 FRSS 在灰度比例尺下测量的 AL，LoA 为 0.019 ± 0.383 mm。FRSS 在伪彩色比例尺下测量的 ACD 最大观察者间变异性的 LoA 为-0.036 ± 0.247 mm。FRSS 在灰度比例尺下测量的 AL 最大观察者内变异性的 LoA 为 0.000 ± 0.157 mm。
与使用 IOLMaster 500 的部分相干干涉测量法相比，使用 FRSS 测序测量 ACD 和 AL 时，其 LoA 和可靠性较高。在 ACD 测量中，FRSS 在伪彩色比例尺下的结果更好，在 AL 测量中，FRSS 在灰度比例尺下的结果更好。由于 AL 测量的变异性，FRSS 不推荐用于 IOL 功率计算。
