Oh Richul, Oh Joo Youn, Choi Hyuk Jin, Kim Mee Kum, Yoon Chang Ho
Department of Ophthalmology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, South Korea.
Department of Ophthalmology, Seoul National University College of Medicine, Seoul, South Korea.
BMC Ophthalmol. 2021 Jan 27;21(1):62. doi: 10.1186/s12886-021-01826-5.
Precise measurement of ocular biometry is critical for determining intraocular lens power. Newly developed swept-source optical coherence tomography (SS-OCT) - based ocular biometric devices, ANTERION and CASIA2 provide ocular biometric measurements as IOLMaster 700. This study aimed to assess agreement between three devices.
This retrospective comparative study includes patients with cataract who underwent ocular biometric measurements with three devices, ANTERION, CASIA2, and IOLMaster 700, at Seoul National University Hospital, in April 2020. Anterior keratometry, total keratometry, central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), and axial length (AL) were the main parameters for the comparison. To assess the agreement between the devices, intraclass coefficient (ICC) and Bland-Altman analysis with 95% limits of agreement (LoA) were used.
A total of 47 eyes of 29 patients were measured with three devices. Average anterior keratometry showed excellent agreement (ICC ≥ 0.989), and the mean difference was less than 0.1 D. However, the ICC of the total average keratometry ranged from 0.808 to 0.952, and the difference was more than 0.43 D. The AL measured by ANTERION and IOLMaster 700 showed excellent agreement (ICC = 0.999), and the mean difference was 0.005 mm. The ANTERION and IOLMaster 700 did not obtain AL in six (12.8%) and three (6.4%) cases, respectively (P = 0.001 by Fisher's exact test). The CCT, ACD, and LT also showed excellent agreement (ICC > 0.9).
The new SS-OCT-based devices, ANTERION, and CASIA2 showed a good agreement with IOLMaster 700 in measuring ocular biometry except for the total keratometry. The AL of ANTERION and IOLMaster 700 showed excellent agreement.
眼生物测量的精确测量对于确定人工晶状体度数至关重要。新开发的基于扫频源光学相干断层扫描（SS-OCT）的眼生物测量设备ANTERION和CASIA2与IOLMaster 700一样可提供眼生物测量。本研究旨在评估这三种设备之间的一致性。
这项回顾性比较研究纳入了2020年4月在首尔国立大学医院接受三种设备（ANTERION、CASIA2和IOLMaster 700）进行眼生物测量的白内障患者。角膜前表面曲率、总角膜曲率、中央角膜厚度（CCT）、前房深度（ACD）、晶状体厚度（LT）和眼轴长度（AL）是主要的比较参数。为评估设备之间的一致性，使用了组内相关系数（ICC）和具有95%一致性界限（LoA）的Bland-Altman分析。
共对29例患者的47只眼使用三种设备进行了测量。平均角膜前表面曲率显示出极佳的一致性（ICC≥0.989），平均差异小于0.1 D。然而，总平均角膜曲率的ICC范围为0.808至0.952，差异超过0.43 D。ANTERION和IOLMaster 700测量的AL显示出极佳的一致性（ICC = 0.999），平均差异为0.005 mm。ANTERION和IOLMaster 700分别在6例（12.8%）和3例（6.4%）病例中未获得AL（Fisher精确检验P = 0.001）。CCT、ACD和LT也显示出极佳的一致性（ICC>0.9）。
新型基于SS-OCT的设备ANTERION和CASIA 在测量眼生物特征方面，除总角膜曲率外，与IOLMaster 700显示出良好的一致性。ANTERION和IOLMaster 700的AL显示出极佳的一致性。
