Epidemiology of Community Origin and Uropathogenic Strains Resistant to Antibiotics in Franceville, Gabon.

INTRODUCTION

Urinary tract infection is one of the major causes of consultation, microbiologic exploration, intensive use of antibiotics worldwide, and the second leading cause of clinical consultation in community practice. Many bacteria play a role in the urinary tract infections etiology, including such as () and spp.

OBJECTIVE

The study's main objective was to examine the epidemiology of and () uropathogenic strains resistant to antibiotics in Franceville.

METHODOLOGY

The study was carried out between January 2018 and June 2019 in Franceville South-East Gabon. We examined a total of 1086 cytobacteriological urine samples. The identification of and strains was carried out using the Vitek-2 compact automated system and the antibiogram with the disk diffusion method according to the European Committee on Antimicrobial Susceptibility Testing recommendations.

RESULTS

The prevalence of urinary tract infections was 29.2% (317/1086), of which 25.1% and 4.1% were mono-infections and co-infections, respectively. The prevalence of UTIs with was 28.7% (91/317) with a predominance of isolation in women. was responsible for 16.2% (61/317) of UTIs. and Uropathogenic strains showed resistance to beta-lactams, quinolones and cotrimoxazole, whereas Nitrofurantoin, Amikacin, Imipenem and Ertapenem were the most active antibiotics against and uropathogenic strains.

CONCLUSION

This study showed a high prevalence of urinary tract infections with a major implication of and strains. and presented high frequency of resistance to antibiotics, highlighting the need to adapt their use accordingly at the local level.