Vasireddy Deepa, Atwi Jibran E
Pediatrics, Pediatric Group of Acadiana, Lafayette, USA.
Cureus. 2021 Jan 21;13(1):e12835. doi: 10.7759/cureus.12835.
Infectious discitis and osteodiscitis in children are rare. The usual age of occurrence is between two and five years. The diagnosis is most often delayed due to mild presenting symptoms. We present the case of a five and half year old child who presented with progressively worsening lower back pain over a period of two weeks, which was made worse with bending forward. He did not have fever, pain in his lower extremities, or any other accompanying symptoms. He did not have a history of recent illnesses or trauma to the lower back. The laboratory work revealed an elevated erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), and rest of the parameters were within normal limits. CT scan of his spine showed findings of well-defined defects on the endplates of L4-L5 with prevertebral soft tissue thickening. MRI with and without contrast of the spine confirmed the findings and detected mild focal erosive changes at the opposing endplates of L4-L5 with disc space narrowing, thin fluid along the anterior margin of the disc, and shallow disc bulging, which were consistent with osteodiscitis. A conservative approach with intravenous antibiotics followed by a switch to oral antibiotics was undertaken with good clinical recovery. Treatment strategy for osteodiscitis in children is generally antibiotic therapy. Prognosis in children is good. In some cases based on the pain severity, other measures such as bed rest, analgesics, and casting for immobilization may be required. Biopsy tends to be reserved in uncertain cases or in those that have poor response to pain control measures and antibiotics.
儿童感染性椎间盘炎和骨椎间盘炎较为罕见。发病的常见年龄在2至5岁之间。由于症状较轻,诊断往往会延迟。我们报告一例5岁半儿童的病例,该患儿在两周内出现下背部疼痛逐渐加重,向前弯腰时疼痛加剧。他没有发热、下肢疼痛或任何其他伴随症状。他近期没有疾病史或下背部外伤史。实验室检查显示红细胞沉降率(ESR)和C反应蛋白(CRP)升高,其余参数均在正常范围内。脊柱CT扫描显示L4-L5椎体终板有边界清晰的缺损,椎前软组织增厚。脊柱增强和未增强MRI均证实了上述发现,并检测到L4-L5相对终板有轻度局灶性侵蚀性改变,椎间盘间隙变窄,椎间盘前缘有少量液体,椎间盘轻度膨出,符合骨椎间盘炎表现。采取了静脉注射抗生素后改为口服抗生素的保守治疗方法,临床恢复良好。儿童骨椎间盘炎的治疗策略通常是抗生素治疗。儿童的预后良好。在某些情况下,根据疼痛严重程度,可能需要采取其他措施,如卧床休息、使用镇痛药和石膏固定。活检往往保留用于诊断不明确的病例或对疼痛控制措施和抗生素反应不佳的病例。