Schittecatte M, Charles G, Depauw Y, Mesters P, Wilmotte J
Department of Psychiatry, Vincent Van Gogh Hospital, Marchienne-au-Pont, Belgium.
Psychiatry Res. 1988 Feb;23(2):147-51. doi: 10.1016/0165-1781(88)90004-2.
The growth hormone (GH) response to clonidine administration (2 micrograms/kg) was compared in three groups of subjects: seven panic disorder patients, seven depressed patients matched for age and sex, and seven normal controls. As previously reported, patients with affective disorders show a blunted GH response to clonidine. Only one panic disorder patient had a blunted GH response to clonidine, and this patient had recently received a tricyclic antidepressant.
在三组受试者中比较了生长激素(GH)对可乐定给药(2微克/千克)的反应:七名惊恐障碍患者、七名年龄和性别匹配的抑郁症患者以及七名正常对照者。如先前报道,情感障碍患者对可乐定的GH反应迟钝。只有一名惊恐障碍患者对可乐定的GH反应迟钝,且该患者最近服用了三环类抗抑郁药。