School of Science (Applied Chemistry and Environmental Science), RMIT University, GPO Box 2476 Melbourne, Victoria 3001, Australia.
Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria 3052, Australia.
J Nat Prod. 2021 Apr 23;84(4):964-971. doi: 10.1021/acs.jnatprod.0c00869. Epub 2021 Feb 25.
Phytochemical profiling was undertaken on the crude extracts of to determine the nature of the chemical constituents present. In total, three new flavonol diglycosides (-), one new flavan-3-ol glycoside (), and 12 previously reported compounds of the flavonol (, ), flavan-3-ol (), flavanone (), 1,4-napthoquinone (, , , ), 2,3-dehydroxynapthalene-1,4-dione (-), and phenolic acid () structure classes were isolated and identified. Compounds -, , , and were assessed for antimicrobial activity, with compounds , , , and showing significant activity. Compounds , , and were also evaluated for anthelmintic activity against larval forms of , with compound being active.
采用植物化学分析方法对 的粗提取物进行分析，以确定其所含化学成分的性质。共分离鉴定了 3 种新的黄酮醇二糖苷（-）、1 种新的黄烷-3-醇糖苷（）和 12 种已报道的黄酮醇（、）、黄烷-3-醇（）、黄烷酮（）、1,4-萘醌（、、、）、2,3-去氢萘-1,4-二酮（-）和酚酸（）类化合物。对化合物 -、-、-、-进行了抗菌活性评估，化合物 -、-、-、-表现出显著的活性。化合物 -、-、-也对 幼虫期进行了驱虫活性评价，化合物 具有活性。
