School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, People's Republic of China.
College of Light Industry and Food Engineering, Nanjing Forestry University, Nanjing, 210037, Jiangsu, People's Republic of China.
Plant Mol Biol. 2021 Jun;106(3):223-238. doi: 10.1007/s11103-021-01128-w. Epub 2021 Feb 25.
This review contains functional roles of NAC transcription factors in the transcriptional regulation of ripening in tomato fruit, describes the interplay between ABA/ethylene and NAC TFs in tomato fruit ripening. Fruit ripening is regulated by a complex network of transcription factors (TFs) and genetic regulators in response to endogenous hormones and external signals. Studying the regulation of fruit ripening has important significance for controlling fruit quality, enhancing nutritional value, improving storage conditions and extending shelf-life. Plant-specific NAC (named after no apical meristem (NAM), Arabidopsis transcription activator factor 1/2 (ATAF1/2) and Cup-shaped cotyledon (CUC2)) TFs play essential roles in plant development, ripening and stress responses. In this review, we summarize the recent progress on the regulation of NAC TFs in fruit ripening, discuss the interactions between NAC and other factors in controlling fruit development and ripening, and emphasize how NAC TFs are involved in tomato fruit ripening through the ethylene and abscisic acid (ABA) pathways. The signaling network regulating ripening is complex, and both hormones and individual TFs can affect the status or activity of other network participants, which can alter the overall ripening network regulation, including response signals and fruit ripening. Our review helps in the systematic understanding of the regulation of NAC TFs involved in fruit ripening and provides a basis for the development or establishment of complex ripening regulatory network models.
本综述包含 NAC 转录因子在番茄果实成熟过程中的转录调控中的功能作用，描述了 ABA/乙烯和 NAC TF 在番茄果实成熟中的相互作用。果实成熟受转录因子 (TF) 和遗传调控因子的复杂网络调控，以响应内源性激素和外部信号。研究果实成熟的调控对控制果实品质、提高营养价值、改善贮藏条件和延长货架期具有重要意义。植物特异性 NAC（以无顶端分生组织 (NAM)、拟南芥转录激活因子 1/2 (ATAF1/2) 和杯状子叶 (CUC2) 命名）TF 在植物发育、成熟和应激反应中发挥重要作用。在本综述中，我们总结了 NAC TF 在果实成熟调控中的最新进展，讨论了 NAC 与其他因素在控制果实发育和成熟中的相互作用，并强调了 NAC TF 如何通过乙烯和脱落酸 (ABA) 途径参与番茄果实成熟。调控成熟的信号网络很复杂，激素和单个 TF 都可以影响其他网络参与者的状态或活性，从而改变整体成熟网络的调控，包括反应信号和果实成熟。我们的综述有助于系统理解参与果实成熟的 NAC TF 的调控，并为复杂成熟调控网络模型的开发或建立提供基础。
