Department of Biotechnology, Radha Govind University, Ramgarh, 829122 Jharkhand, India.
Indian J Tuberc. 2021 Jan;68(1):92-98. doi: 10.1016/j.ijtb.2020.09.021. Epub 2020 Sep 28.
In December 2019, a large number of coronavirus cases were emerged in Wuhan, Hubei Province, China and rapidly spread to different countries and territories around the world within four months. The World Health Organization (WHO) declared this outbreak as a global health emergency. The spread of COVID-19 over globe is highly contagious; they transmitted from person-to-person through small droplets of infected person. Many diagnosis and treatment methods have been implemented to reduce and control the outbreak. Efforts have been made to develop coronavirus vaccine against S protein or spike glycoprotein of coronavirus. COVID-19 outbreak will affect the Gross Domestic Product (GDP) of the world. At the time of preparing manuscript, total number of active cases reaches to more than 8.9 million and confirmed death reaches to approx. 4.6 lakh. This article highlights the ongoing research and advances in designing vaccine and therapeutics against COVID-19 and also focusing on the epidemiology, transmission, future direction and control the spread of infectious diseases.
2019 年 12 月，中国湖北省武汉市出现了大量的冠状病毒病例，并在四个月内迅速传播到世界各地的不同国家和地区。世界卫生组织（WHO）宣布此次疫情为全球卫生紧急事件。COVID-19 在全球范围内高度传染性；它们通过感染者的小飞沫在人与人之间传播。已经实施了许多诊断和治疗方法来减少和控制疫情。人们一直在努力开发针对冠状病毒 S 蛋白或刺突糖蛋白的冠状病毒疫苗。COVID-19 疫情将影响世界国内生产总值（GDP）。在撰写本文时，活跃病例总数已超过 890 万，确诊死亡人数约为 46 万。本文重点介绍了针对 COVID-19 设计疫苗和治疗方法的正在进行的研究和进展，并侧重于传染病的流行病学、传播、未来方向和控制传播。
