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新型冠状病毒肺炎与口腔外科手术:术前漱口液的叙述性综述

COVID-19 and Oral Surgery: A narrative review of preoperative mouth rinses.

作者信息

Testori Tiziano, Wang Hom-Lay, Basso Matteo, Bordini Giordano, Dian Arturo, Vitelli Carlo, Miletic Ivana, Del Fabbro Massimo

机构信息

Department of Implantology and Oral Rehabilitation, IRCCS Istituto Ortopedico Galeazzi, Dental Clinic, Director Prof. L. Francetti, Milan, Italy.

Professor and Director of Graduate Periodontics, Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, Michigan, USA.

出版信息

Acta Stomatol Croat. 2020 Dec;54(4):431-441. doi: 10.15644/asc54/4/10.

Abstract

OBJECTIVE

To provide a narrative review of the preprocedural mouth rinse protocols suggested for oral surgery in order to contrast the presence of SARS-CoV-2 in aerosol.

SOURCES AND METHODS

Electronic searches were performed in medical databases PubMed, Medline, CINAHN and Scopus to identify relevant studies published up until the third week of April 2020. This research was supplemented by exploration through a web-based search engine as well as a manual search for international and national guidelines. Studies and protocols which suggested preoperative mouth rinsing as a recommended measure during the COVID-19 outbreak were included. Given the small number of studies, a narrative literature review was conducted. In total, 15 references (11 articles and 4 guidelines) were considered relevant and were critically analysed.

CONCLUSION

The findings show a high heterogeneity in the protocols suggested. Further research is required to better understand the viral features and epidemiologic characteristics of this new virus and to test the efficacy of commonly used antiseptics against SARS-CoV-2 in future clinical trials. However, the use of chlorhexidine, hydrogen peroxide, PVP-I and cetylpyridinium chloride in contrasting the spread of Covid-19 is described as advisable and substantial in different publications.

摘要

目的

对口腔外科手术前建议使用的漱口方案进行叙述性综述,以对比气溶胶中严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的存在情况。

资料与方法

在医学数据库PubMed、Medline、CINAHL和Scopus中进行电子检索,以识别截至2020年4月第三周发表的相关研究。通过网络搜索引擎进行探索以及手动检索国际和国家指南对本研究进行补充。纳入在2019冠状病毒病(COVID-19)疫情期间建议术前漱口作为推荐措施的研究和方案。鉴于研究数量较少,进行了叙述性文献综述。总共15篇参考文献(11篇文章和4份指南)被认为相关并进行了批判性分析。

结论

研究结果显示所建议的方案存在高度异质性。需要进一步研究以更好地了解这种新病毒的病毒特征和流行病学特征,并在未来临床试验中测试常用防腐剂对SARS-CoV-2的疗效。然而,在不同出版物中,使用洗必泰、过氧化氢、聚维酮碘和氯化十六烷基吡啶来对比COVID-19的传播被认为是可取且重要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fec8/7871429/dd79030113d3/ASC_54(4)_431-441-f1.jpg

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