Kheruka Subhash Chand, Ora Manish, Chaudhary Shivani, Gambhir Sanjay
Department of Nuclear Medicine, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Indian J Nucl Med. 2020 Oct-Dec;35(4):310-314. doi: 10.4103/ijnm.IJNM_44_20. Epub 2020 Oct 21.
Liver volume measurement is a mandatory test before measure liver surgeries and transplantation. We aimed a study on the difference in volume measurement and radiation dose to an anthropomorphic liver phantom using high-dose and low-dose diagnostic computed tomography (CT).
Several measurements of the manual total volume measurement done on an anthropomorphic liver phantom mounted with thermoluminescent dosimeter. We exposed the phantom with diagnostic CT, low-dose CT, and a low-dose CT with copper filter.
Phantom underwent ten scanning for each exposure. There was no significant difference in the total volume measurement in comparison to the phantom volume. The volume of phantom measured by low-dose CT, low-dose CT with copper phantom, and high-dose CT were 1869 ± 18 cm, 1852 ± 24 cm, and 1908 ± 12 cm, ( = 0.3), respectively. However, the radiation dose delivered was significantly different (1.54 mGy, 0.77 mGy, and 5.84 mGy [ = 0.001], respectively).
Total liver volume measurement provides essential clinical information in several clinical conditions. We recommended that the volume measured by a low-dose CT has an excellent correlation with the diagnostic quality CT and should be a routine in the routine clinical practice. CT volumetry achieves the same result while using very less radiation exposure. It may also be used with functional imaging to give complete information.
肝脏体积测量是肝脏手术和移植前的一项必要检查。我们旨在研究使用高剂量和低剂量诊断计算机断层扫描(CT)对拟人化肝脏模型进行体积测量和辐射剂量的差异。
对安装有热释光剂量计的拟人化肝脏模型进行多次手动总体积测量。我们用诊断CT、低剂量CT和带铜滤过器的低剂量CT对模型进行照射。
每次照射模型均进行10次扫描。与模型体积相比,总体积测量无显著差异。低剂量CT、带铜模型的低剂量CT和高剂量CT测量的模型体积分别为1869±18 cm、1852±24 cm和1908±12 cm(P = 0.3)。然而,所给予的辐射剂量有显著差异(分别为1.54 mGy、0.77 mGy和5.84 mGy [P = 0.001])。
全肝体积测量在多种临床情况下提供重要的临床信息。我们建议,低剂量CT测量的体积与诊断质量CT具有良好的相关性,应成为常规临床实践中的常规检查。CT容积测量在使用极少辐射暴露的情况下能获得相同结果。它也可与功能成像一起使用以提供完整信息。