Shah S M Tanjil, Islam Md Tanvir, Zabin Rakiba, Roy Pravas Chandra, Meghla Nigar Sultana, Jahid Iqbal Kabir
Department of Microbiology, Jashore University of Science and Technology, Jashore 7408, Bangladesh.
Vet World. 2021 Jan;14(1):97-103. doi: 10.14202/vetworld.2021.97-103. Epub 2021 Jan 13.
The use of antibiotic growth promoters (AGPs) in the poultry industry has raised concern because of their potential harm to human health. Emerging evidence suggests that probiotics are a safer substitute, although little research has explored this in Bangladesh. We recently isolated local bacterial strains with probiotic properties. We aimed to determine their impact on the growth, hematobiochemical parameters, and production costs of broiler chicks relative to that of a commercial probiotic (CP) and AGP.
Day-old male broiler chicks (Cobb 500, n=63) were divided equally into three experimental groups (three replicates per group and seven chicks per replicate). First group was fed a basal diet supplemented with the AGP, ciprofloxacin (CTL group), second group was fed a basal diet supplemented with the CP, Protexin (CP group), and the third group was fed a basal diet supplemented with our isolated bacterial strains (study probiotic [SP] group) for 36 days. Body weight was recorded daily, and relative growth rate (RGR), feed conversion ratio (FCR), and organ weights and carcass yields were calculated at the study's end. Blood obtained on day 36 was used to determine the number of red blood cell (RBC) and white blood cells (WBCs), hemoglobin (Hb) concentration, packed cell volume, erythrocyte sedimentation rate, as well as levels of serum glucose, total and high-density lipoprotein (HDL) cholesterol, and triglycerides (TGs). Total production costs were estimated by summing the variable and fixed costs.
Chicks in both the CP and SP groups experienced significant decreases in blood glucose levels and significant increases in BW, RGR, FCR, levels of RBC and WBC, Hb concentration, and packed cell volume compared with those in the CTL group (p0.05 for all). Our data suggested a numerical reduction (p>0.05) in levels of total cholesterol, TGs, and HDL in the SP and CP groups when compared to the CTL group. In addition, both CP and SP treatments resulted in significant (p<0.05) gains in net profit compared with the treatment given to the CTL group.
Administration of probiotics, either from a commercialized or local source, led to greater improvements in growth, hematological parameters, and net profits of broiler chicks when compared with that of an AGP. This suggests that they are suitable alternatives to the AGPs used in poultry feed and that our isolated strains, in particular, are an ideal option for farmers in Bangladesh.
家禽养殖业中使用抗生素生长促进剂（AGPs）因其对人类健康的潜在危害而引发关注。新出现的证据表明益生菌是一种更安全的替代品，尽管在孟加拉国对此研究甚少。我们最近分离出了具有益生菌特性的本地细菌菌株。我们旨在确定它们相对于商业益生菌（CP）和AGP对肉鸡生长、血液生化参数及生产成本的影响。
一日龄雄性肉鸡（科宝500，n = 63）被平均分为三个实验组（每组三个重复，每个重复七只鸡）。第一组饲喂添加AGP环丙沙星的基础日粮（CTL组），第二组饲喂添加商业益生菌Protexin的基础日粮（CP组），第三组饲喂添加我们分离出的细菌菌株的基础日粮（研究用益生菌[SP]组），为期36天。每天记录体重，并在研究结束时计算相对生长率（RGR）、饲料转化率（FCR）、器官重量和胴体产量。第36天采集的血液用于测定红细胞（RBC）和白细胞（WBC）数量、血红蛋白（Hb）浓度、血细胞比容、红细胞沉降率，以及血清葡萄糖、总胆固醇和高密度脂蛋白（HDL）胆固醇及甘油三酯（TGs）水平。通过汇总可变成本和固定成本估算总生产成本。
与CTL组相比，CP组和SP组的雏鸡血糖水平显著降低，体重、RGR、FCR、RBC和WBC水平、Hb浓度及血细胞比容显著升高（所有p < 0.05）。我们的数据表明，与CTL组相比，SP组和CP组的总胆固醇、TGs和HDL水平有数值上的降低（p > 0.05）。此外，与CTL组相比，CP组和SP组的净利润均显著增加（p < 0.05）。
与AGP相比，施用商业化或本地来源的益生菌对肉鸡的生长、血液学参数和净利润有更大改善。这表明它们是家禽饲料中AGPs的合适替代品，特别是我们分离出的菌株，对孟加拉国的农民来说是一个理想选择。
