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良性胆囊疾病手术治疗的变化趋势

Changing trends in surgery for benign gallbladder disease.

作者信息

Gutman H, Kott I, Haddad M, Reiss R

机构信息

Department of Surgery B, Beilinson Medical Center, Petah Tiqva, Israel.

出版信息

Am J Gastroenterol. 1988 May;83(5):545-8.

PMID:3364412
Abstract

Hospital charts and notes of 2181 consecutive cholecystectomies performed between 1969 and 1984 were computer analyzed. They were divided into three categories of patients operated on 5, 10, and 15 yr ago. The trends of change throughout this period were as follows: 1) The population operated on in the last 5 yr is older, the proportion of males, especially over 70-80 yr old, and diabetics, is growing constantly. 2) The frequency of acalculous cholecystitis and gangrenous changes increase; the same is true for common bile duct pathology and positive bile cultures. 3) There is a marked decrease in hospitalization time, postoperatively, without significant increase in rate of wound infection and thromboembolic phenomena, or mortality. It seems that there is no change in the frequency of gallstone-related pancreatitis and perforations of gallbladder. The same is disappointingly true for positive choledochal exploration index. We think that the subcostal approach, with rational prophylactic and therapeutic antibiotic regimen, contribute to the shortening of hospitalization time and the fixed rates of wound infection and herniae in scar. Prophylactic heparin given subcutaneously seems to avoid possible thromboembolic phenomena.

摘要

对1969年至1984年间连续进行的2181例胆囊切除术的医院病历和记录进行了计算机分析。这些病例被分为三类,分别是5年、10年和15年前接受手术的患者。在此期间的变化趋势如下:1)过去5年接受手术的患者群体年龄更大,男性比例,尤其是70至80岁以上男性以及糖尿病患者的比例在持续增加。2)无结石性胆囊炎和坏疽性改变的发生率增加;胆总管病变和胆汁培养阳性的情况也是如此。3)术后住院时间显著缩短,而伤口感染率、血栓栓塞现象发生率或死亡率均无显著增加。胆结石相关胰腺炎和胆囊穿孔的发生率似乎没有变化。令人失望的是,胆总管探查阳性率也是如此。我们认为,采用肋下入路,结合合理的预防性和治疗性抗生素方案,有助于缩短住院时间,并使伤口感染率和瘢痕疝发生率保持稳定。皮下注射预防性肝素似乎可以避免可能出现的血栓栓塞现象。

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