Rassi Yavar, Moradi-Asl Eslam, Vatandoost Hassan, Abazari Malek, Saghafipour Abedin
Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Department of Public Health, School of Public Health, Ardabil University of Medical Sciences, Ardabil, Iran.
J Arthropod Borne Dis. 2020 Sep 30;14(3):277-285. doi: 10.18502/jad.v14i3.4561. eCollection 2020 Sep.
and sand flies are the vectors of visceral leishmaniasis in Iran. The aim of this study was to evaluate the susceptibility of and , collected from an endemic focus of visceral leishmaniasis (VL) in the northwest of Iran, to different selected insecticides.
Sand flies were collected from the villages of Meshkinshahr and Germi Counties using light traps and aspirators from May to October 2019. The sand flies were identified as and using standard identification keys. Susceptibility test was carried out against DDT (4%), Malathion (5%), Propoxur (0.1%) and Lambda-cyhalothrin (0.05%) according to the WHO standard method. MedCalc statistical software was employed to calculate LT and LT and to compare the chances of sand flies surviving the exposure to the studied insecticides.
A total of 1,278 female specimens were used for the susceptibility tests. Out of which 1,063 samples were used for the test and 215 for the control group. The estimated LT values for DDT (4%), Malathion (5%), Propoxur (0.1%), and Lambda-cyhalothrin (0.05%) for were 15.1, 13.4, 15.4 and 5.8 minutes respectively, and for were 11.9, 15.6, 15.9 and 5.8 minutes respectively.
This susceptibility studies revealed different LT values for different insecticides efficient against and . The regular monitoring for the resistance of and sand flies seems necessary in diseases control programs in this area.
白蛉是伊朗内脏利什曼病的传播媒介。本研究的目的是评估从伊朗西北部内脏利什曼病（VL）流行区采集的白蛉对不同选定杀虫剂的敏感性。
2019年5月至10月，使用诱虫灯和吸虫器从Meshkinshahr和Germi县的村庄采集白蛉。根据标准鉴定方法将白蛉鉴定为[具体白蛉种类1]和[具体白蛉种类2]。按照世界卫生组织标准方法，对白蛉进行了对滴滴涕（4%）、马拉硫磷（5%）、残杀威（0.1%）和高效氯氟氰菊酯（0.05%）的敏感性测试。使用MedCalc统计软件计算半数致死时间（LT）50和LT90，并比较白蛉在接触所研究杀虫剂后存活的几率。
总共1278只雌性标本用于敏感性测试。其中1063个样本用于测试，215个用于对照组。[具体白蛉种类1]对滴滴涕（4%）、马拉硫磷（5%）、残杀威（0.1%）和高效氯氟氰菊酯（0.05%）的估计LT50值分别为15.1、13.4、15.4和5.8分钟，[具体白蛉种类2]的分别为11.9、15.6、15.9和5.8分钟。
这项敏感性研究揭示了对[具体白蛉种类1]和[具体白蛉种类2]有效的不同杀虫剂的不同LT值。在该地区的疾病控制项目中，对白蛉抗性进行定期监测似乎很有必要。
