Jaiswal Shubham K, Mahajan Shruti, Chakraborty Abhisek, Kumar Sudhir, Sharma Vineet K
MetaBioSys Group, Department of Biological Sciences, Indian Institute of Science Education and Research Bhopal, Bhopal, Madhya Pradesh, India.
iScience. 2021 Jan 21;24(2):102079. doi: 10.1016/j.isci.2021.102079. eCollection 2021 Feb 19.
is a species from Asphodelaceae family having characteristics like drought resistance and numerous medicinal properties. However, the genetic basis of these phenotypes is yet unknown primarily due to unavailability of its genome sequence. Thus, we report the first genome sequence comprising of 12.93 Gbp and harboring 86,177 protein-coding genes. It is the first genome from Asphodelaceae family and the largest angiosperm genome sequenced and assembled till date. We also report the first genome-wide phylogeny of monocots including to resolve its phylogenetic position. The comprehensive comparative analysis of with other available high-quality monocot genomes revealed adaptive evolution in several genes of drought stress response, CAM pathway, and circadian rhythm and positive selection in DNA damage response genes in . This study provides clues on the genetic basis of evolution of drought stress tolerance capabilities of .
是天门冬科的一个物种,具有抗旱等特性和多种药用特性。然而,由于其基因组序列不可用,这些表型的遗传基础尚不清楚。因此,我们报告了第一个基因组序列,其大小为12.93 Gbp,包含86177个蛋白质编码基因。它是天门冬科的第一个基因组,也是迄今为止测序和组装的最大被子植物基因组。我们还报告了单子叶植物的首个全基因组系统发育研究,包括以确定其系统发育位置。与其他可用的高质量单子叶植物基因组进行的全面比较分析揭示了在干旱胁迫响应、景天酸代谢途径和昼夜节律的几个基因中的适应性进化,以及在其DNA损伤响应基因中的正选择。本研究为其干旱胁迫耐受能力进化的遗传基础提供了线索。