Department of Gynecology and Obstetrics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, PR China.
Gynecol Endocrinol. 2021 Jul;37(7):655-659. doi: 10.1080/09513590.2021.1892629. Epub 2021 Mar 1.
The aim of this study was to evaluate the relationship between the severity of menopausal symptoms and everyday cognitive decline in Chinese peri and postmenopausal women.
The peri and postmenopausal Chinese Han female who first visited the menopausal clinic of Shanghai Jiao Tong University Affiliated Sixth People's Hospital was selected as the study participants. The general questionnaire was used to obtain the sociodemographic characteristics of the study participants. The menopausal rating scale (MRS) was used to assess the severity of menopausal symptoms. The short version of the Everyday Cognition (ECog-12) scales was used to assess everyday cognitive performance.
A total of 295 women were included, with an average age of 51.12 ± 5.15 years. The average ECog scores were 1.51 ± 0.49 and the average MRS scores were 6.89 ± 4.77. In multiple linear regression analysis, after adjusting for confounding factors age, body mass index (BMI), monthly income, occupational status, education level, menopausal status, parity, regular exercise, and history of chronic diseases, complaints of anxiety and physical/mental fatigue were positively correlated with everyday cognitive decline.
Menopausal anxiety and physical/mental fatigue were the independent predictors of everyday cognition.
本研究旨在评估中国绝经前后女性的更年期症状严重程度与日常认知衰退之间的关系。
选取首次就诊于上海交通大学附属第六人民医院更年期门诊的中国汉族绝经前后女性作为研究对象。采用一般问卷获取研究对象的社会人口学特征。采用更年期评定量表(MRS)评估更年期症状严重程度。采用简易认知量表(ECog-12)评估日常认知表现。
共纳入 295 名女性,平均年龄 51.12±5.15 岁。平均 ECog 评分为 1.51±0.49,平均 MRS 评分为 6.89±4.77。在多线性回归分析中,校正年龄、体质指数(BMI)、月收入、职业状况、教育水平、绝经状态、产次、规律运动和慢性病史等混杂因素后,焦虑和躯体/精神疲劳的主诉与日常认知下降呈正相关。
更年期焦虑和躯体/精神疲劳是日常认知的独立预测因素。