Department for Management of Science and Technology Development, Ton Duc Thang University, Ho Chi Minh City, Viet Nam; Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City, Viet Nam.
Department of Biology, Science Faculty, Selcuk University, Campus, 42130, Konya, Turkey.
Food Res Int. 2021 Feb;140:110068. doi: 10.1016/j.foodres.2020.110068. Epub 2020 Dec 25.
Geophytes are gaining interest as sources of natural ingredients in nutraceutical and pharmaceutical area. In this sense, six bulbous plant species from Turkey are investigated, namely Hyacinthella campanulata K.Perss. & Wendelbo, Muscari neglectum Guss. ex Ten., Tulipa humilis herb., Iris stenophylla Hausskn. ex Baker, Galanthus elwesii Hook. f. and Crocus danfordiae Maw. with the aim to highlight their chemical compositions and biological properties. Polyphenolic profiles of the different plant parts (flower, bulb and leaf) of the six genotypes were evaluated using colorimetric methods as well LC-MS/MS. The antioxidant properties and enzymes inhibitory potential (α-amylase, α-glucosidase, tyrosinase and cholinesterases) of the extracts were determined. Overall, highest total phenolic content and total flavonoid content were observed in the leaf extracts of the studied species, except for M. neglectum (flower extract) and T. humilis (flower extract). LC-MS/MS analysis revealed the abundance of some phenolic compounds including quinic acid, hesperidin and chlorogenic acid in selective extracts. The extracts showed significant antioxidant potentials, with leaf extract of the I. stenophylla being more potent, which is linked to its high phenolic contents. All the extracts displayed notable anti-acetylcholinesterase (1.77 - 2.53 mg GALAE/g) and tyrosinase (54.9-67.20 mg KAE/g). Selective extracts have showed activity against butyrylcholinesterase, with bulb extract of M. neglectum (2.99 mg GALAE/g), I. stenophylla (2.53 mg GALAE/g) and G. elwesii (2.52 mg GALAE/g) showing highest activity. Modest activity was observed against α-amylase and α-glucosidase. The experimental data gathered herein is the first report on the phytochemical and biological attributes of these bulbous plant species which project them as potential sources of biologically active compounds for phytomedicines and nutraceuticals development.
球茎植物因其在营养保健品和制药领域作为天然成分的来源而受到关注。在这方面，对来自土耳其的六种鳞茎植物物种进行了研究，分别为 Hyacinthella campanulata K.Perss. & Wendelbo、Muscari neglectum Guss. ex Ten.、Tulipa humilis herb.、Iris stenophylla Hausskn. ex Baker、Galanthus elwesii Hook. f. 和 Crocus danfordiae Maw.，旨在突出它们的化学成分和生物特性。使用比色法和 LC-MS/MS 评估了六种基因型的不同植物部位（花、鳞茎和叶）的多酚谱。测定了提取物的抗氧化性能和酶抑制潜力（α-淀粉酶、α-葡萄糖苷酶、酪氨酸酶和胆碱酯酶）。总的来说，在所研究的物种中，除了 M. neglectum（花提取物）和 T. humilis（花提取物）之外，叶提取物的总酚含量和总类黄酮含量最高。LC-MS/MS 分析显示，在选择性提取物中存在一些酚类化合物，包括奎宁酸、橙皮苷和绿原酸。提取物表现出显著的抗氧化潜力，其中 I. stenophylla 的叶提取物更为有效，这与其高酚含量有关。所有提取物均表现出显著的抗乙酰胆碱酯酶（1.77-2.53 mg GALAE/g）和酪氨酸酶（54.9-67.20 mg KAE/g）活性。选择性提取物对丁酰胆碱酯酶具有活性，其中 M. neglectum（2.99 mg GALAE/g）、I. stenophylla（2.53 mg GALAE/g）和 G. elwesii（2.52 mg GALAE/g）的鳞茎提取物活性最高。对α-淀粉酶和α-葡萄糖苷酶表现出适度的活性。本文收集的实验数据首次报道了这些鳞茎植物物种的植物化学和生物学特性，这些特性使它们成为植物药和营养保健品开发中具有生物活性化合物的潜在来源。
