Crouch J D, Keagy B A, Starek P J, Delany D J, Wilcox B R
Department of Surgery, University of North Carolina, Chapel Hill.
Am Surg. 1988 May;54(5):297-9.
Both the radiology and surgery literature mention "popcorn calcification" as a diagnostic aid in identifying pulmonary hamartomas. Nineteen patients underwent resection of pulmonary hamartomas at North Carolina Memorial Hospital between January 1969 and February 1983, representing 1.9 per cent of all thoracotomies performed for pulmonary disease. Of the 19 patients, there were 12 men (63%) and 7 women (37%), and most were asymptomatic. Chest x-ray demonstrated 12 right-sided and 7 left-sided lesions. All masses were located peripherally in the lung parenchyma and in no instance was calcification present. Fourteen wedge resections and 5 lobectomies were performed. Pathologic examination confirmed the absence of calcification; however, in two cases (11%) an associated malignancy was present. There were no operative deaths and only minor postoperative complications. All problems resolved without difficulty. These data show that pulmonary hamartomas are not commonly associated with calcification, and there may be an increased association with carcinoma of the lung. Excision can be performed with minimal morbidity and is necessary to distinguish hamartomas from malignant lesions.
放射学和外科学文献均提及“爆米花样钙化”可作为鉴别肺错构瘤的诊断依据。1969年1月至1983年2月期间,北卡罗来纳纪念医院有19例患者接受了肺错构瘤切除术,占因肺部疾病而行开胸手术患者总数的1.9%。这19例患者中,男性12例(63%),女性7例(37%),多数患者无症状。胸部X线显示右侧病变12例,左侧病变7例。所有肿块均位于肺实质周边,均未出现钙化。实施了14例楔形切除术和5例肺叶切除术。病理检查证实无钙化;然而,有2例(11%)伴有恶性肿瘤。无手术死亡病例,术后仅出现轻微并发症。所有问题均顺利解决。这些数据表明,肺错构瘤通常不伴有钙化,且可能与肺癌的相关性增加。切除手术可将发病率降至最低,对于鉴别错构瘤与恶性病变很有必要。