Department of Chemistry, Kookmin University, 77 Jeongneung-ro, Seongbuk-gu, Seoul 02707, Republic of Korea.
Department of Plant and Environmental New Resources, Graduate School of Biotechnology, Institute of Life Sciences and Resources, Kyung Hee University, 1732 Deogyeong-daero, Giheung-gu, Yongin-si, Gyeonggi-do, 446-701, Republic of Korea.
J Hazard Mater. 2021 Jul 15;414:125160. doi: 10.1016/j.jhazmat.2021.125160. Epub 2021 Jan 14.
Surface-enhanced Raman scattering (SERS) has proven to be a valuable tool for assessing harmful chemicals in various substances, including water, soil, and foods. However, a fast measurement system is required for multiplexed detection to extend the range of its applications. The rotating scanning stage of the SERS substrate is considered to be a promising approach to achieving a fast measurement system. This paper reports a facile measurement system by using a flexible nanocellulose-based SERS substrate and a spiral scanning system, which rotates the cylinder sample holder and moves the stage. A flexible nanocellulose-based SERS substrate deposited with Au nanoparticles is suitable for the spiral scanning system, which requires SERS substrates to be highly flexible and durable. The well-known toxic fungicide, thiram, was tested by this system. The results revealed that the nanocellulose-based SERS substrate is well-fitted with a spiral scanning system and that the signal data from a large area substrate can be obtained within 30 s. It is noteworthy that the error of spiral scanning measurements is smaller than that of multi-spot sampling. This work provides a powerful tool for Raman spectroscopic analysis, which requires quantitative and fast testing. Furthermore, various flexible SERS substrates can be utilized in this system for toxic materials detection.
表面增强拉曼散射（SERS）已被证明是一种评估水、土壤和食品等各种物质中有害化学物质的有用工具。然而，为了扩展其应用范围，需要一个快速的测量系统来进行多重检测。SERS 基底的旋转扫描台被认为是实现快速测量系统的一种很有前途的方法。本文报道了一种通过使用基于纳米纤维素的柔性 SERS 基底和螺旋扫描系统来实现简便测量的系统，该系统可以旋转圆柱样品架并移动平台。一种沉积有 Au 纳米颗粒的基于纳米纤维素的 SERS 基底适用于螺旋扫描系统，因为该系统要求 SERS 基底具有高度的灵活性和耐用性。该系统测试了著名的有毒杀菌剂福美双。结果表明，基于纳米纤维素的 SERS 基底与螺旋扫描系统非常匹配，并且可以在 30 秒内获得来自大面积基底的信号数据。值得注意的是，螺旋扫描测量的误差小于多点采样的误差。这项工作为需要定量和快速测试的拉曼光谱分析提供了一个强大的工具。此外，该系统还可以利用各种柔性 SERS 基底来检测有毒材料。
