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倍半萜内酯和二萜类化合物：传染病、肿瘤及其他慢性疾病的潜在治疗候选物。

Sesquiterpene Lactones and Diterpenes: Promising Therapeutic Candidates for Infectious Diseases, Neoplasms and Other Chronic Disorders.

作者信息

Sülsen Valeria P

机构信息

Instituto de Química y Metabolismo del Fármaco (IQUIMEFA), CONICET-Universidad de Buenos Aires, 1113 Buenos Aires, Argentina.

Cátedra de Farmacognosia, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, 1113 Buenos Aires, Argentina.

出版信息

Molecules. 2021 Feb 26;26(5):1251. doi: 10.3390/molecules26051251.

DOI:10.3390/molecules26051251
PMID:33652593
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7956199/
Abstract

Nature is an important source for the discovery of new bioactive compounds [...].

摘要

自然界是发现新的生物活性化合物的重要来源[……]。

相似文献

[1]
Sesquiterpene Lactones and Diterpenes: Promising Therapeutic Candidates for Infectious Diseases, Neoplasms and Other Chronic Disorders.

Molecules. 2021-2-26

[2]
Sesquiterpene lactones from Saussurea involucrata.

Fitoterapia. 2011-5-27

[3]
Neurobiological Promises of the Bitter Diterpene Lactone Andrographolide.

Oxid Med Cell Longev. 2022

[4]
Germacranolide-type sesquiterpene lactones from Smallanthus sonchifolius with promising activity against Leishmania mexicana and Trypanosoma cruzi.

Parasit Vectors. 2017-11-13

[5]
New cytotoxic sesquiterpene lactones from Warionia saharae.

Planta Med. 2003-5

[6]
Sesquiterpene lactones from Crepis cameroonica (Asteraceae).

Nat Prod Res. 2006-5-10

[7]
[Treatment of peptic ulcer with alanton].

Vrach Delo. 1978-6

[8]
Perspectives on sesquiterpene lactones in inflammation and cancer.

Curr Drug Targets. 2011-10

[9]
Cytotoxic triterpene and sesquiterpene lactones from Elephantopus mollis and induction of apoptosis in neuroblastoma cells.

Planta Med. 2007-4

[10]
Sesquiterpene lactones. Part XI. Studies on the cytotoxic effect of alatolide on the human lymphocytes and neoplastic cells in tissue culture.

Pol J Pharmacol Pharm. 1974

引用本文的文献

[1]
Aubl. Essential Oil: Chemical Composition and Emerging Biological Activities.

Molecules. 2025-8-8

[2]
Xanthatin nanocrystals exert anti-inflammatory properties against TNFα-primed 2D monolayers and in 3D spheroids of human HT29 colorectal cancer cells.

Discov Nano. 2025-5-19

[3]
Functional Redundancy and Dual Function of a Hypothetical Protein in the Biosynthesis of Eunicellane-Type Diterpenoids.

ACS Chem Biol. 2024-11-15

[4]
Diterpenes: An Updated Review Concerning Their Structural Diversity, Therapeutic Performance, and Future Pharmaceutical Applications.

Pharmaceuticals (Basel). 2024-10-19

[5]
Enhancing Ocular Surface in Dry Eye Disease Patients: A Clinical Evaluation of a Topical Formulation Containing Sesquiterpene Lactone Helenalin.

Pharmaceuticals (Basel). 2024-1-30

[6]
Antiparasitic Effects of Asteraceae Species Extracts on s.s.

Evid Based Complement Alternat Med. 2022-9-19

[7]
Anthelmintic activity of extract against .

Parasitology. 2022-4

本文引用的文献

[1]
Andrographolide and Its 14-Aryloxy Analogues Inhibit Zika and Dengue Virus Infection.

Molecules. 2020-10-30

[2]
Synthesis, Crystallography, and Anti-Leukemic Activity of the Amino Adducts of Dehydroleucodine.

Molecules. 2020-10-20

[3]
Trypanocidal Activity of Four Sesquiterpene Lactones Isolated from Asteraceae Species.

Molecules. 2020-4-25

[4]
Antitumor activity and mechanism of costunolide and dehydrocostus lactone: Two natural sesquiterpene lactones from the Asteraceae family.

Biomed Pharmacother. 2020-1-31

[5]
Lychnopholide in Poly(d,l-Lactide)--Polyethylene Glycol Nanocapsules Cures Infection with a Drug-Resistant Strain at Acute and Chronic Phases.

Antimicrob Agents Chemother. 2020-3-24

[6]
Medically Useful Plant Terpenoids: Biosynthesis, Occurrence, and Mechanism of Action.

Molecules. 2019-11-1

[7]
Natural Sesquiterpene Lactones of the 4,15--Atriplicolide Type are Inhibitors of Trypanothione Reductase.

Molecules. 2019-10-16

[8]
Activity of the sesquiterpene lactone goyazensolide against and .

Parasitology. 2019-9-23

[9]
Macrocyclic Diterpenoids from Euphorbiaceae as A Source of Potent and Selective Inhibitors of Chikungunya Virus Replication.

Molecules. 2019-6-25

[10]
Preparation of Sesquiterpene Lactone-Loaded PLA Nanoparticles and Evaluation of Their Antitrypanosomal Activity.

Molecules. 2019-6-4

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