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用于对抗传染性病原体的银纳米颗粒基纳米复合材料：最新进展与未来展望

Silver Nanoparticle-Based Nanocomposites for Combating Infectious Pathogens: Recent Advances and Future Prospects.

作者信息

Wahab Md A, Li Luming, Li Hongmei, Abdala Ahmed

机构信息

Institute for Advanced Study, Chengdu University, Chengdu 610106, China.

College of Food and Biological Engineering, Chengdu University, Chengdu 610106, China.

出版信息

Nanomaterials (Basel). 2021 Feb 26;11(3):581. doi: 10.3390/nano11030581.

DOI:10.3390/nano11030581
PMID:33652693
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7996865/
Abstract

Silver nanoparticles (Ag NPs) and their nanocomposites with polymers are potent agents for antibacterial and disinfectant applications. The structural parameters of Ag-NPs, such as size, shape, and surface area, are very critical for developing appropriate formulations for the targeted applications. The impact of these factors on the performance of Ag NPs is analyzed. Ag NPs with a broad spectrum of antibacterial activities have already found applications in wound and burn dressing, food preservation, agricultural ponds, treatment for infected areas, coatings, water treatment, and other biomedical applications. Ag NPs are quite useful against antibiotic-resistant bacteria, but their level of toxicity needs careful investigation as their toxicity could be very harmful to human health and the environment. This review discusses the challenges and prospects of various Ag NPs and their composites. The review will enrich the knowledge about the efficiency and mechanism of various Ag nanoparticle-based antibacterial agents.

摘要

银纳米颗粒（Ag NPs）及其与聚合物的纳米复合材料是用于抗菌和消毒应用的有效剂。Ag-NPs的结构参数，如尺寸、形状和表面积，对于开发适用于目标应用的配方非常关键。分析了这些因素对Ag NPs性能的影响。具有广谱抗菌活性的Ag NPs已在伤口和烧伤敷料、食品保鲜、农业池塘、感染区域治疗、涂层、水处理及其他生物医学应用中得到应用。Ag NPs对耐抗生素细菌相当有效，但其毒性水平需要仔细研究，因为它们的毒性可能对人类健康和环境非常有害。本综述讨论了各种Ag NPs及其复合材料的挑战和前景。该综述将丰富有关各种基于银纳米颗粒的抗菌剂的效率和作用机制的知识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c5/7996865/24b3df4cd855/nanomaterials-11-00581-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c5/7996865/a894664d28d7/nanomaterials-11-00581-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c5/7996865/34d66e414296/nanomaterials-11-00581-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c5/7996865/686c22e56311/nanomaterials-11-00581-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c5/7996865/943ae52a2838/nanomaterials-11-00581-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c5/7996865/3a13e06f2b11/nanomaterials-11-00581-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c5/7996865/091e660be11f/nanomaterials-11-00581-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c5/7996865/0513c30d4b32/nanomaterials-11-00581-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c5/7996865/24b3df4cd855/nanomaterials-11-00581-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c5/7996865/a894664d28d7/nanomaterials-11-00581-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c5/7996865/34d66e414296/nanomaterials-11-00581-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c5/7996865/686c22e56311/nanomaterials-11-00581-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c5/7996865/943ae52a2838/nanomaterials-11-00581-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c5/7996865/3a13e06f2b11/nanomaterials-11-00581-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c5/7996865/091e660be11f/nanomaterials-11-00581-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c5/7996865/0513c30d4b32/nanomaterials-11-00581-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3c5/7996865/24b3df4cd855/nanomaterials-11-00581-g008.jpg

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