Pereira Leonel, Valado Ana
Department of Life Sciences, University of Coimbra, 3000-456 Coimbra, Portugal.
MARE-Marine and Environmental Sciences Centre, Faculty of Science and Technology, University of Coimbra, 3000-548 Coimbra, Portugal.
Mar Drugs. 2021 Feb 26;19(3):128. doi: 10.3390/md19030128.
Edible marine algae are rich in bioactive compounds and are, therefore, a source of bioavailable proteins, long chain polysaccharides that behave as low-calorie soluble fibers, metabolically necessary minerals, vitamins, polyunsaturated fatty acids, and antioxidants. Marine algae were used primarily as gelling agents and thickeners (phycocolloids) in food and pharmaceutical industries in the last century, but recent research has revealed their potential as a source of useful compounds for the pharmaceutical, medical, and cosmetic industries. The green, red, and brown algae have been shown to have useful therapeutic properties in the prevention and treatment of neurodegenerative diseases: Parkinson, Alzheimer's, and Multiple Sclerosis, and other chronic diseases. In this review are listed and described the main components of a suitable diet for patients with these diseases. In addition, compounds derived from macroalgae and their neurophysiological activities are described.
可食用海藻富含生物活性化合物,因此是生物可利用蛋白质、具有低热量可溶性纤维特性的长链多糖、代谢必需矿物质、维生素、多不饱和脂肪酸和抗氧化剂的来源。上个世纪,海藻主要用作食品和制药行业的胶凝剂和增稠剂(藻胶),但最近的研究揭示了它们作为制药、医疗和化妆品行业有用化合物来源的潜力。绿色、红色和棕色海藻已被证明在预防和治疗神经退行性疾病(帕金森病、阿尔茨海默病和多发性硬化症)以及其他慢性疾病方面具有有益的治疗特性。本综述列出并描述了适合这些疾病患者的饮食的主要成分。此外,还描述了源自大型海藻的化合物及其神经生理活性。